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Compounds that modulate AMPK activity and hepatic steatosis impact the biosynthesis of microRNAs required to maintain lipid homeostasis in hepatocytes.
Latorre J, Ortega FJ, Liñares-Pose L, Moreno-Navarrete JM, Lluch A, Comas F, Oliveras-Cañellas N, Ricart W, Höring M, Zhou Y, Liebisch G, Nidhina Haridas PA, Olkkonen VM, López M, Fernández-Real JM. Latorre J, et al. Among authors: horing m. EBioMedicine. 2020 Mar;53:102697. doi: 10.1016/j.ebiom.2020.102697. Epub 2020 Mar 3. EBioMedicine. 2020. PMID: 32143184 Free PMC article.
Human adipocyte differentiation and composition of disease-relevant lipids are regulated by miR-221-3p.
Ahonen MA, Asghar MY, Parviainen SJ, Liebisch G, Höring M, Leidenius M, Fischer-Posovszky P, Wabitsch M, Mikkola TS, Törnquist K, Savolainen-Peltonen H, Haridas PAN, Olkkonen VM. Ahonen MA, et al. Among authors: horing m. Biochim Biophys Acta Mol Cell Biol Lipids. 2021 Jan;1866(1):158841. doi: 10.1016/j.bbalip.2020.158841. Epub 2020 Oct 16. Biochim Biophys Acta Mol Cell Biol Lipids. 2021. PMID: 33075494
Absence of nuclear receptors LXRs impairs immune response to androgen deprivation and leads to prostate neoplasia.
Bousset L, Septier A, Bunay J, Voisin A, Guiton R, Damon-Soubeyrant C, Renaud Y, De Haze A, Sapin V, Fogli A, Rambur A, De Joussineau C, Kocer A, Trousson A, Henry-Berger J, Höring M, Liebisch G, Matysik S, Lobaccaro JA, Morel L, Baron S. Bousset L, et al. Among authors: horing m. PLoS Biol. 2020 Dec 7;18(12):e3000948. doi: 10.1371/journal.pbio.3000948. eCollection 2020 Dec. PLoS Biol. 2020. PMID: 33284790 Free PMC article.
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