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A prolonged exposure of human lung carcinoma epithelial cells to benzo[a]pyrene induces p21-dependent epithelial-to-mesenchymal transition (EMT)-like phenotype.
Hýžďalová M, Procházková J, Strapáčová S, Svržková L, Vacek O, Fedr R, Andrysík Z, Hrubá E, Líbalová H, Kléma J, Topinka J, Mašek J, Souček K, Vondráček J, Machala M. Hýžďalová M, et al. Chemosphere. 2021 Jan;263:128126. doi: 10.1016/j.chemosphere.2020.128126. Epub 2020 Sep 10. Chemosphere. 2021. PMID: 33297115
Adaptive changes in global gene expression profile of lung carcinoma A549 cells acutely exposed to distinct types of AhR ligands.
Procházková J, Strapáčová S, Svržková L, Andrysík Z, Hýžďalová M, Hrubá E, Pěnčíková K, Líbalová H, Topinka J, Kléma J, Espinosa JM, Vondráček J, Machala M. Procházková J, et al. Among authors: hyzdalova m. Toxicol Lett. 2018 Aug;292:162-174. doi: 10.1016/j.toxlet.2018.04.024. Epub 2018 Apr 25. Toxicol Lett. 2018. PMID: 29704546
Changes in Sphingolipid Profile of Benzo[a]pyrene-Transformed Human Bronchial Epithelial Cells Are Reflected in the Altered Composition of Sphingolipids in Their Exosomes.
Machala M, Slavík J, Kováč O, Procházková J, Pěnčíková K, Pařenicová M, Straková N, Kotouček J, Kulich P, Mollerup S, Vondráček J, Hýžďalová M. Machala M, et al. Among authors: hyzdalova m. Int J Mol Sci. 2021 Aug 25;22(17):9195. doi: 10.3390/ijms22179195. Int J Mol Sci. 2021. PMID: 34502101 Free PMC article.
In vitro profiling of toxic effects of prominent environmental lower-chlorinated PCB congeners linked with endocrine disruption and tumor promotion.
Pěnčíková K, Svržková L, Strapáčová S, Neča J, Bartoňková I, Dvořák Z, Hýžďalová M, Pivnička J, Pálková L, Lehmler HJ, Li X, Vondráček J, Machala M. Pěnčíková K, et al. Among authors: hyzdalova m. Environ Pollut. 2018 Jun;237:473-486. doi: 10.1016/j.envpol.2018.02.067. Epub 2018 Mar 15. Environ Pollut. 2018. PMID: 29518658 Free PMC article.
Environmental six-ring polycyclic aromatic hydrocarbons are potent inducers of the AhR-dependent signaling in human cells.
Vondráček J, Pěnčíková K, Ciganek M, Pivnička J, Karasová M, Hýžďalová M, Strapáčová S, Pálková L, Neča J, Matthews J, Lom MV, Topinka J, Milcová A, Machala M. Vondráček J, et al. Among authors: hyzdalova m. Environ Pollut. 2020 Nov;266(Pt 2):115125. doi: 10.1016/j.envpol.2020.115125. Epub 2020 Jul 3. Environ Pollut. 2020. PMID: 32679438
17 results