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Platelet Gi protein Gαi2 is an essential mediator of thrombo-inflammatory organ damage in mice.
Devanathan V, Hagedorn I, Köhler D, Pexa K, Cherpokova D, Kraft P, Singh M, Rosenberger P, Stoll G, Birnbaumer L, Piekorz RP, Beer-Hammer S, Nieswandt B, Nürnberg B. Devanathan V, et al. Among authors: hagedorn i. Proc Natl Acad Sci U S A. 2015 May 19;112(20):6491-6. doi: 10.1073/pnas.1505887112. Epub 2015 May 5. Proc Natl Acad Sci U S A. 2015. PMID: 25944935 Free PMC article.
Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature.
Kleinschnitz C, Kraft P, Dreykluft A, Hagedorn I, Göbel K, Schuhmann MK, Langhauser F, Helluy X, Schwarz T, Bittner S, Mayer CT, Brede M, Varallyay C, Pham M, Bendszus M, Jakob P, Magnus T, Meuth SG, Iwakura Y, Zernecke A, Sparwasser T, Nieswandt B, Stoll G, Wiendl H. Kleinschnitz C, et al. Among authors: hagedorn i. Blood. 2013 Jan 24;121(4):679-91. doi: 10.1182/blood-2012-04-426734. Epub 2012 Nov 15. Blood. 2013. PMID: 23160472 Free PMC article.
Combined in vivo depletion of glycoprotein VI and C-type lectin-like receptor 2 severely compromises hemostasis and abrogates arterial thrombosis in mice.
Bender M, May F, Lorenz V, Thielmann I, Hagedorn I, Finney BA, Vögtle T, Remer K, Braun A, Bösl M, Watson SP, Nieswandt B. Bender M, et al. Among authors: hagedorn i. Arterioscler Thromb Vasc Biol. 2013 May;33(5):926-34. doi: 10.1161/ATVBAHA.112.300672. Epub 2013 Feb 28. Arterioscler Thromb Vasc Biol. 2013. PMID: 23448972 Free PMC article.
37 results