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Dasatinib can Impair Left Ventricular Mechanical Function But May Lack Proarrhythmic Effect: A Proposal of Non-clinical Guidance for Predicting Clinical Cardiovascular Adverse Events of Tyrosine Kinase Inhibitors.
Izumi-Nakaseko H, Fujiyoshi M, Hagiwara-Nagasawa M, Goto A, Chiba K, Kambayashi R, Naito AT, Ando K, Kanda Y, Ishii I, Sugiyama A. Izumi-Nakaseko H, et al. Cardiovasc Toxicol. 2020 Feb;20(1):58-70. doi: 10.1007/s12012-019-09538-5. Cardiovasc Toxicol. 2020. PMID: 31280457
Measurement of J-Tpeakc along with QT-Interval Prolongation May Increase the Assay Sensitivity and Specificity for Predicting the Onset of Drug-Induced Torsade de Pointes: Experimental Evidences Based on Proarrhythmia Model Animals.
Goto A, Hagiwara-Nagasawa M, Kambayashi R, Chiba K, Izumi-Nakaseko H, Naito AT, Kanda Y, Sugiyama A. Goto A, et al. Cardiovasc Toxicol. 2019 Aug;19(4):357-364. doi: 10.1007/s12012-019-09506-z. Cardiovasc Toxicol. 2019. PMID: 30712162
45 results