Haigis KM - Search Results

1

Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon.

Haigis KM, Kendall KR, Wang Y, Cheung A, Haigis MC, Glickman JN, Niwa-Kawakita M, Sweet-Cordero A, Sebolt-Leopold J, Shannon KM, Settleman J, Giovannini M, Jacks T. Haigis KM, et al. Among authors: haigis mc. Nat Genet. 2008 May;40(5):600-8. doi: 10.1038/ng.115. Epub 2008 Mar 30. Nat Genet. 2008. PMID: 18372904 Free PMC article.

2

Haigis K, Sage J, Glickman J, Shafer S, Jacks T. Haigis K, et al. J Biol Chem. 2006 Jan 6;281(1):638-47. doi: 10.1074/jbc.M509053200. Epub 2005 Oct 28. J Biol Chem. 2006. PMID: 16258171 Free article.

3

SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells.

Haigis MC, Mostoslavsky R, Haigis KM, Fahie K, Christodoulou DC, Murphy AJ, Valenzuela DM, Yancopoulos GD, Karow M, Blander G, Wolberger C, Prolla TA, Weindruch R, Alt FW, Guarente L. Haigis MC, et al. Among authors: haigis km. Cell. 2006 Sep 8;126(5):941-54. doi: 10.1016/j.cell.2006.06.057. Cell. 2006. PMID: 16959573 Free article.

4

Oncogenic K-RAS subverts the antiapoptotic role of N-RAS and alters modulation of the N-RAS:gelsolin complex.

Keller JW, Haigis KM, Franklin JL, Whitehead RH, Jacks T, Coffey RJ. Keller JW, et al. Among authors: haigis km. Oncogene. 2007 May 10;26(21):3051-9. doi: 10.1038/sj.onc.1210103. Epub 2006 Nov 20. Oncogene. 2007. PMID: 17130841

5

Requirement for Rac1 in a K-ras induced lung cancer in the mouse.

Kissil JL, Walmsley MJ, Hanlon L, Haigis KM, Bender Kim CF, Sweet-Cordero A, Eckman MS, Tuveson DA, Capobianco AJ, Tybulewicz VL, Jacks T. Kissil JL, et al. Among authors: haigis km. Cancer Res. 2007 Sep 1;67(17):8089-94. doi: 10.1158/0008-5472.CAN-07-2300. Cancer Res. 2007. PMID: 17804720

6

E2F1 represses beta-catenin transcription and is antagonized by both pRB and CDK8.

Morris EJ, Ji JY, Yang F, Di Stefano L, Herr A, Moon NS, Kwon EJ, Haigis KM, Näär AM, Dyson NJ. Morris EJ, et al. Among authors: haigis km. Nature. 2008 Sep 25;455(7212):552-6. doi: 10.1038/nature07310. Epub 2008 Sep 14. Nature. 2008. PMID: 18794899 Free PMC article.

7

RAS mutations affect tumor necrosis factor-induced apoptosis in colon carcinoma cells via ERK-modulatory negative and positive feedback circuits along with non-ERK pathway effects.

Kreeger PK, Mandhana R, Alford SK, Haigis KM, Lauffenburger DA. Kreeger PK, et al. Among authors: haigis km. Cancer Res. 2009 Oct 15;69(20):8191-9. doi: 10.1158/0008-5472.CAN-09-1921. Epub 2009 Sep 29. Cancer Res. 2009. PMID: 19789336 Free PMC article.

8

Non-redundancy within the RAS oncogene family: insights into mutational disparities in cancer.

Lau KS, Haigis KM. Lau KS, et al. Among authors: haigis km. Mol Cells. 2009 Oct 31;28(4):315-20. doi: 10.1007/s10059-009-0143-7. Epub 2009 Sep 30. Mol Cells. 2009. PMID: 19812895 Free PMC article. Review.

9

Complete deletion of Apc results in severe polyposis in mice.

Cheung AF, Carter AM, Kostova KK, Woodruff JF, Crowley D, Bronson RT, Haigis KM, Jacks T. Cheung AF, et al. Among authors: haigis km. Oncogene. 2010 Mar 25;29(12):1857-64. doi: 10.1038/onc.2009.457. Epub 2009 Dec 14. Oncogene. 2010. PMID: 20010873 Free PMC article.

10

p53 controls radiation-induced gastrointestinal syndrome in mice independent of apoptosis.

Kirsch DG, Santiago PM, di Tomaso E, Sullivan JM, Hou WS, Dayton T, Jeffords LB, Sodha P, Mercer KL, Cohen R, Takeuchi O, Korsmeyer SJ, Bronson RT, Kim CF, Haigis KM, Jain RK, Jacks T. Kirsch DG, et al. Among authors: haigis km. Science. 2010 Jan 29;327(5965):593-6. doi: 10.1126/science.1166202. Epub 2009 Dec 17. Science. 2010. PMID: 20019247 Free PMC article.

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