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A novel Huntington's disease mouse model to assess the role of neuroinflammation on disease progression and to develop human cell therapies.
Dahlenburg H, Cameron D, Yang S, Bachman A, Pollock K, Cary W, Pham M, Hendrix K, White J, Nelson H, Deng P, Anderson JS, Fink K, Nolta J. Dahlenburg H, et al. Among authors: nelson h. Stem Cells Transl Med. 2021 Jul;10(7):1033-1043. doi: 10.1002/sctm.20-0431. Epub 2021 Mar 12. Stem Cells Transl Med. 2021. PMID: 33710799 Free PMC article.
Human Mesenchymal Stem Cells Genetically Engineered to Overexpress Brain-derived Neurotrophic Factor Improve Outcomes in Huntington's Disease Mouse Models.
Pollock K, Dahlenburg H, Nelson H, Fink KD, Cary W, Hendrix K, Annett G, Torrest A, Deng P, Gutierrez J, Nacey C, Pepper K, Kalomoiris S, D Anderson J, McGee J, Gruenloh W, Fury B, Bauer G, Duffy A, Tempkin T, Wheelock V, Nolta JA. Pollock K, et al. Among authors: nelson h. Mol Ther. 2016 May;24(5):965-77. doi: 10.1038/mt.2016.12. Epub 2016 Jan 14. Mol Ther. 2016. PMID: 26765769 Free PMC article.