Hall SD - Search Results

1

Pharmacogenomics of gemcitabine metabolism: functional analysis of genetic variants in cytidine deaminase and deoxycytidine kinase.

Baker JA, Wickremsinhe ER, Li CH, Oluyedun OA, Dantzig AH, Hall SD, Qian YW, Ring BJ, Wrighton SA, Guo Y. Baker JA, et al. Among authors: hall sd. Drug Metab Dispos. 2013 Mar;41(3):541-5. doi: 10.1124/dmd.112.048769. Epub 2012 Dec 10. Drug Metab Dispos. 2013. PMID: 23230131

2

Comparative metabolic capabilities of CYP3A4, CYP3A5, and CYP3A7.

Williams JA, Ring BJ, Cantrell VE, Jones DR, Eckstein J, Ruterbories K, Hamman MA, Hall SD, Wrighton SA. Williams JA, et al. Among authors: hall sd. Drug Metab Dispos. 2002 Aug;30(8):883-91. doi: 10.1124/dmd.30.8.883. Drug Metab Dispos. 2002. PMID: 12124305

3

Differential modulation of UDP-glucuronosyltransferase 1A1 (UGT1A1)-catalyzed estradiol-3-glucuronidation by the addition of UGT1A1 substrates and other compounds to human liver microsomes.

Williams JA, Ring BJ, Cantrell VE, Campanale K, Jones DR, Hall SD, Wrighton SA. Williams JA, et al. Among authors: hall sd. Drug Metab Dispos. 2002 Nov;30(11):1266-73. doi: 10.1124/dmd.30.11.1266. Drug Metab Dispos. 2002. PMID: 12386134

4

Prediction of in vivo clearance and associated variability of CYP2C19 substrates by genotypes in populations utilizing a pharmacogenetics-based mechanistic model.

Steere B, Baker JA, Hall SD, Guo Y. Steere B, et al. Among authors: hall sd. Drug Metab Dispos. 2015 Jun;43(6):870-83. doi: 10.1124/dmd.114.061523. Epub 2015 Apr 6. Drug Metab Dispos. 2015. PMID: 25845826

5

Stochastic prediction of CYP3A-mediated inhibition of midazolam clearance by ketoconazole.

Chien JY, Lucksiri A, Ernest CS 2nd, Gorski JC, Wrighton SA, Hall SD. Chien JY, et al. Among authors: hall sd. Drug Metab Dispos. 2006 Jul;34(7):1208-19. doi: 10.1124/dmd.105.008730. Epub 2006 Apr 12. Drug Metab Dispos. 2006. PMID: 16611859

6

Prediction of CYP3A-mediated drug-drug interactions using human hepatocytes suspended in human plasma.

Mao J, Mohutsky MA, Harrelson JP, Wrighton SA, Hall SD. Mao J, et al. Among authors: hall sd. Drug Metab Dispos. 2011 Apr;39(4):591-602. doi: 10.1124/dmd.110.036400. Epub 2011 Jan 6. Drug Metab Dispos. 2011. PMID: 21212240 Free article.

7

Predictions of cytochrome P450-mediated drug-drug interactions using cryopreserved human hepatocytes: comparison of plasma and protein-free media incubation conditions.

Mao J, Mohutsky MA, Harrelson JP, Wrighton SA, Hall SD. Mao J, et al. Among authors: hall sd. Drug Metab Dispos. 2012 Apr;40(4):706-16. doi: 10.1124/dmd.111.043158. Epub 2012 Jan 6. Drug Metab Dispos. 2012. PMID: 22228749

8

CYP2B6 pharmacogenetics-based in vitro-in vivo extrapolation of efavirenz clearance by physiologically based pharmacokinetic modeling.

Xu C, Quinney SK, Guo Y, Hall SD, Li L, Desta Z. Xu C, et al. Among authors: hall sd. Drug Metab Dispos. 2013 Dec;41(12):2004-11. doi: 10.1124/dmd.113.051755. Epub 2013 Jul 11. Drug Metab Dispos. 2013. PMID: 23846872 Free PMC article. Clinical Trial.

9

Abemaciclib Does Not Have a Clinically Meaningful Effect on Pharmacokinetics of CYP1A2, CYP2C9, CYP2D6, and CYP3A4 Substrates in Patients with Cancer.

Turner PK, Hall SD, Chapman SC, Rehmel JL, Royalty JE, Guo Y, Kulanthaivel P. Turner PK, et al. Among authors: hall sd. Drug Metab Dispos. 2020 Sep;48(9):796-803. doi: 10.1124/dmd.119.090092. Epub 2020 Jun 24. Drug Metab Dispos. 2020. PMID: 32581049 Clinical Trial.

10

Autoactivation and activation of the cytochrome P450s.

Ekins S, Ring BJ, Binkley SN, Hall SD, Wrighton SA. Ekins S, et al. Among authors: hall sd. Int J Clin Pharmacol Ther. 1998 Dec;36(12):642-51. Int J Clin Pharmacol Ther. 1998. PMID: 9877001

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