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High-throughput analysis of behavior for drug discovery.
Alexandrov V, Brunner D, Hanania T, Leahy E. Alexandrov V, et al. Among authors: hanania t. Eur J Pharmacol. 2015 Mar 5;750:82-9. doi: 10.1016/j.ejphar.2014.11.047. Epub 2015 Jan 12. Eur J Pharmacol. 2015. PMID: 25592319 Free PMC article. Review.
Comprehensive analysis of two Shank3 and the Cacna1c mouse models of autism spectrum disorder.
Kabitzke PA, Brunner D, He D, Fazio PA, Cox K, Sutphen J, Thiede L, Sabath E, Hanania T, Alexandrov V, Rasmusson R, Spooren W, Ghosh A, Feliciano P, Biemans B, Benedetti M, Clayton AL. Kabitzke PA, et al. Among authors: hanania t. Genes Brain Behav. 2018 Jan;17(1):4-22. doi: 10.1111/gbb.12405. Epub 2017 Sep 5. Genes Brain Behav. 2018. PMID: 28753255 Free article.
The potent and selective α4β2*/α6*-nicotinic acetylcholine receptor partial agonist 2-[5-[5-((S)Azetidin-2-ylmethoxy)-3-pyridinyl]-3-isoxazolyl]ethanol demonstrates antidepressive-like behavior in animal models and a favorable ADME-tox profile.
Yu LF, Brek Eaton J, Zhang HK, Sabath E, Hanania T, Li GN, van Breemen RB, Whiteaker P, Liu Q, Wu J, Chang YC, Lukas RJ, Brunner D, Kozikowski AP. Yu LF, et al. Among authors: hanania t. Pharmacol Res Perspect. 2014 Apr;2(2):e00026. doi: 10.1002/prp2.26. Epub 2014 Mar 12. Pharmacol Res Perspect. 2014. PMID: 25505580 Free PMC article.
Comprehensive Analysis of the 16p11.2 Deletion and Null Cntnap2 Mouse Models of Autism Spectrum Disorder.
Brunner D, Kabitzke P, He D, Cox K, Thiede L, Hanania T, Sabath E, Alexandrov V, Saxe M, Peles E, Mills A, Spooren W, Ghosh A, Feliciano P, Benedetti M, Luo Clayton A, Biemans B. Brunner D, et al. Among authors: hanania t. PLoS One. 2015 Aug 14;10(8):e0134572. doi: 10.1371/journal.pone.0134572. eCollection 2015. PLoS One. 2015. PMID: 26273832 Free PMC article.
Discovery of highly potent and selective α4β2-nicotinic acetylcholine receptor (nAChR) partial agonists containing an isoxazolylpyridine ether scaffold that demonstrate antidepressant-like activity. Part II.
Yu LF, Eaton JB, Fedolak A, Zhang HK, Hanania T, Brunner D, Lukas RJ, Kozikowski AP. Yu LF, et al. Among authors: hanania t. J Med Chem. 2012 Nov 26;55(22):9998-10009. doi: 10.1021/jm301177j. Epub 2012 Nov 2. J Med Chem. 2012. PMID: 23092294 Free PMC article.
59 results