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PurA is the main target of aurodox, a type III secretion system inhibitor.
Watanabe Y, Haneda T, Kimishima A, Kuwae A, Suga T, Suzuki T, Iwabuchi Y, Honsho M, Honma S, Iwatsuki M, Matsui H, Hanaki H, Kanoh N, Abe A, Asami Y, Ōmura S. Watanabe Y, et al. Among authors: haneda t. Proc Natl Acad Sci U S A. 2024 Apr 23;121(17):e2322363121. doi: 10.1073/pnas.2322363121. Epub 2024 Apr 19. Proc Natl Acad Sci U S A. 2024. PMID: 38640341
Vi polysaccharide and conjugated vaccines afford similar early, IgM or IgG-independent control of infection but boosting with conjugated Vi vaccines sustains the efficacy of immune responses.
Jossi SE, Arcuri M, Alshayea A, Persaud RR, Marcial-Juárez E, Palmieri E, Di Benedetto R, Pérez-Toledo M, Pillaye J, Channell WM, Schager AE, Lamerton RE, Cook CN, Goodall M, Haneda T, Bäumler AJ, Jackson-Jones LH, Toellner KM, MacLennan CA, Henderson IR, Micoli F, Cunningham AF. Jossi SE, et al. Among authors: haneda t. Front Immunol. 2023 Mar 23;14:1139329. doi: 10.3389/fimmu.2023.1139329. eCollection 2023. Front Immunol. 2023. PMID: 37033932 Free PMC article.
O-acetylesterase activity of Bifidobacterium bifidum sialidase facilities the liberation of sialic acid and encourages the proliferation of sialic acid scavenging Bifidobacterium breve.
Yokoi T, Nishiyama K, Kushida Y, Uribayashi K, Kunihara T, Fujimoto R, Yamamoto Y, Ito M, Miki T, Haneda T, Mukai T, Okada N. Yokoi T, et al. Among authors: haneda t. Environ Microbiol Rep. 2022 Aug;14(4):637-645. doi: 10.1111/1758-2229.13083. Epub 2022 May 17. Environ Microbiol Rep. 2022. PMID: 35581157
Virulence factors perforate the pathogen-containing vacuole to signal efferocytosis.
Hiyoshi H, English BC, Diaz-Ochoa VE, Wangdi T, Zhang LF, Sakaguchi M, Haneda T, Tsolis RM, Bäumler AJ. Hiyoshi H, et al. Among authors: haneda t. Cell Host Microbe. 2022 Feb 9;30(2):163-170.e6. doi: 10.1016/j.chom.2021.12.001. Epub 2021 Dec 23. Cell Host Microbe. 2022. PMID: 34951948 Free PMC article.
197 results