Hanquet G - Search Results

1

Novel CLK1 inhibitors based on N-aryloxazol-2-amine skeleton - A possible way to dual VEGFR2 TK/CLK ligands.

Murár M, Dobiaš J, Šramel P, Addová G, Hanquet G, Boháč A. Murár M, et al. Among authors: hanquet g. Eur J Med Chem. 2017 Jan 27;126:754-761. doi: 10.1016/j.ejmech.2016.11.003. Epub 2016 Nov 18. Eur J Med Chem. 2017. PMID: 27940419

2

Ynamide Click chemistry in development of triazole VEGFR2 TK modulators.

Vojtičková M, Dobiaš J, Hanquet G, Addová G, Cetin-Atalay R, Yildirim DC, Boháč A. Vojtičková M, et al. Among authors: hanquet g. Eur J Med Chem. 2015 Oct 20;103:105-22. doi: 10.1016/j.ejmech.2015.08.012. Epub 2015 Aug 8. Eur J Med Chem. 2015. PMID: 26344911

3

Synthesis, biological evaluation and molecular modeling studies on novel quinonoid inhibitors of CDC25 phosphatases.

Evain-Bana E, Schiavo L, Bour C, Lanfranchi DA, Berardozzi S, Ghirga F, Bagrel D, Botta B, Hanquet G, Mori M. Evain-Bana E, et al. Among authors: hanquet g. J Enzyme Inhib Med Chem. 2017 Dec;32(1):113-118. doi: 10.1080/14756366.2016.1238364. Epub 2016 Oct 23. J Enzyme Inhib Med Chem. 2017. PMID: 27774816 Free PMC article.

4

Quinoides and VEGFR2 TKIs influence the fate of hepatocellular carcinoma and its cancer stem cells.

Kahraman DC, Hanquet G, Jeanmart L, Lanners S, Šramel P, Boháč A, Cetin-Atalay R. Kahraman DC, et al. Among authors: hanquet g. Medchemcomm. 2016 Oct 7;8(1):81-87. doi: 10.1039/c6md00392c. eCollection 2017 Jan 1. Medchemcomm. 2016. PMID: 30108693 Free PMC article.

5

Development of Novel Oxotriazinoindole Inhibitors of Aldose Reductase: Isosteric Sulfur/Oxygen Replacement in the Thioxotriazinoindole Cemtirestat Markedly Improved Inhibition Selectivity.

Hlaváč M, Kováčiková L, Prnová MŠ, Šramel P, Addová G, Májeková M, Hanquet G, Boháč A, Štefek M. Hlaváč M, et al. Among authors: hanquet g. J Med Chem. 2020 Jan 9;63(1):369-381. doi: 10.1021/acs.jmedchem.9b01747. Epub 2019 Dec 30. J Med Chem. 2020. PMID: 31820975

6

Novel substituted N-benzyl(oxotriazinoindole) inhibitors of aldose reductase exploiting ALR2 unoccupied interactive pocket.

Hlaváč M, Kováčiková L, Šoltésová Prnová M, Addová G, Hanquet G, Štefek M, Boháč A. Hlaváč M, et al. Among authors: hanquet g. Bioorg Med Chem. 2021 Jan 1;29:115885. doi: 10.1016/j.bmc.2020.115885. Epub 2020 Nov 22. Bioorg Med Chem. 2021. PMID: 33271452

7

Design, synthesis and biological evaluation of antimicrobial diarylimine and -amine compounds targeting the interaction between the bacterial NusB and NusE proteins.

Qiu Y, Chan ST, Lin L, Shek TL, Tsang TF, Barua N, Zhang Y, Ip M, Chan PK, Blanchard N, Hanquet G, Zuo Z, Yang X, Ma C. Qiu Y, et al. Among authors: hanquet g. Eur J Med Chem. 2019 Sep 15;178:214-231. doi: 10.1016/j.ejmech.2019.05.090. Epub 2019 Jun 3. Eur J Med Chem. 2019. PMID: 31185412

8

Access to Wieland-Miescher Diketone-Derived Building Blocks by Stereoselective Construction of the C-9 Quaternary Carbon Center Using the Mukaiyama Aldol Reaction.

Schiavo L, Lebedel L, Massé P, Choppin S, Hanquet G. Schiavo L, et al. Among authors: hanquet g. J Org Chem. 2018 Jun 15;83(12):6247-6258. doi: 10.1021/acs.joc.7b02862. Epub 2018 Mar 30. J Org Chem. 2018. PMID: 29601190

9

Asymmetric Diels-Alder reactions of a new enantiomerically pure sulfinylquinone: a straightforward access to functionalized Wieland-Miescher ketone analogues with (R) absolute configuration.

Lanfranchi DA, Hanquet G. Lanfranchi DA, et al. Among authors: hanquet g. J Org Chem. 2006 Jun 23;71(13):4854-61. doi: 10.1021/jo060486n. J Org Chem. 2006. PMID: 16776513

10

Nusbiarylins, a new class of antimicrobial agents: Rational design of bacterial transcription inhibitors targeting the interaction between the NusB and NusE proteins.

Qiu Y, Chan ST, Lin L, Shek TL, Tsang TF, Zhang Y, Ip M, Chan PK, Blanchard N, Hanquet G, Zuo Z, Yang X, Ma C. Qiu Y, et al. Among authors: hanquet g. Bioorg Chem. 2019 Nov;92:103203. doi: 10.1016/j.bioorg.2019.103203. Epub 2019 Aug 16. Bioorg Chem. 2019. PMID: 31446238

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