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Mitochondrial accumulation of APP and Abeta: significance for Alzheimer disease pathogenesis.
J Cell Mol Med. 2009 Oct;13(10):4137-45. doi: 10.1111/j.1582-4934.2009.00892.x. Epub 2009 Sep 1.
J Cell Mol Med. 2009.
PMID: 19725915
Free PMC article.
Review.
The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae.
Hansson Petersen CA, Alikhani N, Behbahani H, Wiehager B, Pavlov PF, Alafuzoff I, Leinonen V, Ito A, Winblad B, Glaser E, Ankarcrona M.
Hansson Petersen CA, et al.
Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):13145-50. doi: 10.1073/pnas.0806192105. Epub 2008 Aug 29.
Proc Natl Acad Sci U S A. 2008.
PMID: 18757748
Free PMC article.
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