Hao Q - Search Results

1

UDP-glucuronosyltransferase (UGT) 2B15 pharmacogenetics: UGT2B15 D85Y genotype and gender are major determinants of oxazepam glucuronidation by human liver.

Court MH, Hao Q, Krishnaswamy S, Bekaii-Saab T, Al-Rohaimi A, von Moltke LL, Greenblatt DJ. Court MH, et al. Among authors: hao q. J Pharmacol Exp Ther. 2004 Aug;310(2):656-65. doi: 10.1124/jpet.104.067660. Epub 2004 Mar 25. J Pharmacol Exp Ther. 2004. PMID: 15044558

2

Evaluation of 3'-azido-3'-deoxythymidine, morphine, and codeine as probe substrates for UDP-glucuronosyltransferase 2B7 (UGT2B7) in human liver microsomes: specificity and influence of the UGT2B7*2 polymorphism.

Court MH, Krishnaswamy S, Hao Q, Duan SX, Patten CJ, Von Moltke LL, Greenblatt DJ. Court MH, et al. Among authors: hao q. Drug Metab Dispos. 2003 Sep;31(9):1125-33. doi: 10.1124/dmd.31.9.1125. Drug Metab Dispos. 2003. PMID: 12920168

3

Pharmacogenetic determinants of interindividual variability in bupropion hydroxylation by cytochrome P450 2B6 in human liver microsomes.

Hesse LM, He P, Krishnaswamy S, Hao Q, Hogan K, von Moltke LL, Greenblatt DJ, Court MH. Hesse LM, et al. Among authors: hao q. Pharmacogenetics. 2004 Apr;14(4):225-38. doi: 10.1097/00008571-200404000-00002. Pharmacogenetics. 2004. PMID: 15083067

4

Evaluation of 5-hydroxytryptophol and other endogenous serotonin (5-hydroxytryptamine) analogs as substrates for UDP-glucuronosyltransferase 1A6.

Krishnaswamy S, Hao Q, Von Moltke LL, Greenblatt DJ, Court MH. Krishnaswamy S, et al. Among authors: hao q. Drug Metab Dispos. 2004 Aug;32(8):862-9. doi: 10.1124/dmd.32.8.862. Drug Metab Dispos. 2004. PMID: 15258112

5

UDP glucuronosyltransferase (UGT) 1A6 pharmacogenetics: II. Functional impact of the three most common nonsynonymous UGT1A6 polymorphisms (S7A, T181A, and R184S).

Krishnaswamy S, Hao Q, Al-Rohaimi A, Hesse LM, von Moltke LL, Greenblatt DJ, Court MH. Krishnaswamy S, et al. Among authors: hao q. J Pharmacol Exp Ther. 2005 Jun;313(3):1340-6. doi: 10.1124/jpet.104.081968. Epub 2005 Mar 10. J Pharmacol Exp Ther. 2005. PMID: 15761113

6

UDP glucuronosyltransferase (UGT) 1A6 pharmacogenetics: I. Identification of polymorphisms in the 5'-regulatory and exon 1 regions, and association with human liver UGT1A6 gene expression and glucuronidation.

Krishnaswamy S, Hao Q, Al-Rohaimi A, Hesse LM, von Moltke LL, Greenblatt DJ, Court MH. Krishnaswamy S, et al. Among authors: hao q. J Pharmacol Exp Ther. 2005 Jun;313(3):1331-9. doi: 10.1124/jpet.104.081950. Epub 2005 Mar 10. J Pharmacol Exp Ther. 2005. PMID: 15761114

7

Identification of common polymorphisms in the promoter of the UGT1A9 gene: evidence that UGT1A9 protein and activity levels are strongly genetically controlled in the liver.

Girard H, Court MH, Bernard O, Fortier LC, Villeneuve L, Hao Q, Greenblatt DJ, von Moltke LL, Perussed L, Guillemette C. Girard H, et al. Among authors: hao q. Pharmacogenetics. 2004 Aug;14(8):501-15. doi: 10.1097/01.fpc.0000114754.08559.27. Pharmacogenetics. 2004. PMID: 15284532

8

UGT1A1 polymorphisms are important determinants of dietary carcinogen detoxification in the liver.

Girard H, Thibaudeau J, Court MH, Fortier LC, Villeneuve L, Caron P, Hao Q, von Moltke LL, Greenblatt DJ, Guillemette C. Girard H, et al. Among authors: hao q. Hepatology. 2005 Aug;42(2):448-57. doi: 10.1002/hep.20770. Hepatology. 2005. PMID: 15986396

9

The novel UGT1A9 intronic I399 polymorphism appears as a predictor of 7-ethyl-10-hydroxycamptothecin glucuronidation levels in the liver.

Girard H, Villeneuve L, Court MH, Fortier LC, Caron P, Hao Q, von Moltke LL, Greenblatt DJ, Guillemette C. Girard H, et al. Among authors: hao q. Drug Metab Dispos. 2006 Jul;34(7):1220-8. doi: 10.1124/dmd.106.009787. Epub 2006 Apr 4. Drug Metab Dispos. 2006. PMID: 16595709

10

Role of the nuclear receptor pregnane X receptor in acetaminophen hepatotoxicity.

Wolf KK, Wood SG, Hunt JA, Walton-Strong BW, Yasuda K, Lan L, Duan SX, Hao Q, Wrighton SA, Jeffery EH, Evans RM, Szakacs JG, von Moltke LL, Greenblatt DJ, Court MH, Schuetz EG, Sinclair PR, Sinclair JF. Wolf KK, et al. Among authors: hao q. Drug Metab Dispos. 2005 Dec;33(12):1827-36. doi: 10.1124/dmd.105.005256. Epub 2005 Sep 1. Drug Metab Dispos. 2005. PMID: 16141365

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