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Small molecule nitroalkenes inhibit RAD51-mediated homologous recombination and amplify triple-negative breast cancer cell killing by DNA-directed therapies.
Hong L, Braden DC, Zhao Y, Skoko JJ, Chang F, Woodcock SR, Uvalle C, Casey A, Wood K, Salvatore SR, Asan A, Harkness T, Fagunloye A, Razzaghi M, Straub A, Spies M, Brown DD, Lee AV, Schopfer F, Freeman BA, Neumann CA. Hong L, et al. Among authors: harkness t. bioRxiv [Preprint]. 2023 Aug 14:2023.08.11.552990. doi: 10.1101/2023.08.11.552990. bioRxiv. 2023. PMID: 37645906 Free PMC article. Updated. Preprint.
Small molecule nitroalkenes inhibit RAD51-mediated homologous recombination and amplify triple-negative breast cancer cell killing by DNA-directed therapies.
Hong L, Braden DC, Zhao Y, Skoko JJ, Chang F, Woodcock SR, Uvalle C, Casey A, Wood K, Salvatore SR, Asan A, Harkness T, Fagunloye A, Razzaghi M, Straub A, Spies M, Brown DD, Lee AV, Schopfer F, Freeman BA, Neumann CA. Hong L, et al. Among authors: harkness t. Redox Biol. 2023 Oct;66:102856. doi: 10.1016/j.redox.2023.102856. Epub 2023 Aug 19. Redox Biol. 2023. PMID: 37633047 Free PMC article.
Assessment of patient-reported symptoms and distress in IgG4-related disease (IgG4-RD): Development, clinical validation, and content validation of the IgG4-RD Symptom Severity Index.
Wallace ZS, McMahon GA, Hang B, Fu X, Harkness T, Donelan K, Fernandes A, Cook C, Katz G, Perugino C, Stone JH. Wallace ZS, et al. Among authors: harkness t. Semin Arthritis Rheum. 2023 Dec;63:152253. doi: 10.1016/j.semarthrit.2023.152253. Epub 2023 Aug 18. Semin Arthritis Rheum. 2023. PMID: 37619485
Activation of the Anaphase Promoting Complex Reverses Multiple Drug Resistant Cancer in a Canine Model of Multiple Drug Resistant Lymphoma.
Arnason TG, MacDonald-Dickinson V, Gaunt MC, Davies GF, Lobanova L, Trost B, Gillespie ZE, Waldner M, Baldwin P, Borrowman D, Marwood H, Vizeacoumar FS, Vizeacoumar FJ, Eskiw CH, Kusalik A, Harkness TAA. Arnason TG, et al. Among authors: harkness taa. Cancers (Basel). 2022 Aug 30;14(17):4215. doi: 10.3390/cancers14174215. Cancers (Basel). 2022. PMID: 36077749 Free PMC article.
Redox regulation of RAD51 Cys319 and homologous recombination by peroxiredoxin 1.
Skoko JJ, Cao J, Gaboriau D, Attar M, Asan A, Hong L, Paulsen CE, Ma H, Liu Y, Wu H, Harkness T, Furdui CM, Manevich Y, Morrison CG, Brown ET, Normolle D, Spies M, Spies MA, Carroll K, Neumann CA. Skoko JJ, et al. Among authors: harkness t. Redox Biol. 2022 Oct;56:102443. doi: 10.1016/j.redox.2022.102443. Epub 2022 Aug 24. Redox Biol. 2022. PMID: 36058112 Free PMC article.
The Covid communicators.
Harkness T. Harkness T. Signif (Oxf). 2022 Apr;19(2):26-29. doi: 10.1111/1740-9713.01631. Epub 2022 Mar 29. Signif (Oxf). 2022. PMID: 35601696 Free PMC article.
Smc5/6 in the rDNA modulates lifespan independently of Fob1​.
Moradi-Fard S, Mojumdar A, Chan M, Harkness TAA, Cobb JA. Moradi-Fard S, et al. Among authors: harkness taa. Aging Cell. 2021 Jun;20(6):e13373. doi: 10.1111/acel.13373. Epub 2021 May 12. Aging Cell. 2021. PMID: 33979898 Free PMC article.
"'The scientific method' doesn't leave you".
Harkness T. Harkness T. Signif (Oxf). 2021 Feb;18(1):32-35. doi: 10.1111/1740-9713.01489. Epub 2021 Feb 3. Signif (Oxf). 2021. PMID: 33821161 Free PMC article.
77 results