Harmat NJ - Search Results

1

Discovery of a new series of potent and selective linear tachykinin NK2 receptor antagonists.

Fedi V, Altamura M, Catalioto RM, Giannotti D, Giolitti A, Giuliani S, Guidi A, Harmat NJ, Lecci A, Meini S, Nannicini R, Pasqui F, Tramontana M, Triolo A, Maggi CA. Fedi V, et al. Among authors: harmat nj. J Med Chem. 2007 Oct 4;50(20):4793-807. doi: 10.1021/jm070289w. Epub 2007 Sep 12. J Med Chem. 2007. PMID: 17850056

2

Insertion of 2-carboxysuccinate and tricarballylic acid fragments into cyclic-pseudopeptides: new antagonists for the human tachykinin NK-2 receptor.

Harmat NJ, Giannotti D, Nannicini R, Perrotta E, Criscuoli M, Patacchini R, Renzetti AR, Giuliani S, Altamura M, Maggi CA. Harmat NJ, et al. Bioorg Med Chem Lett. 2002 Feb 25;12(4):693-6. doi: 10.1016/s0960-894x(01)00841-1. Bioorg Med Chem Lett. 2002. PMID: 11844703

3

Insertion of an aspartic acid moiety into cyclic pseudopeptides: synthesis and biological characterization of potent antagonists for the human Tachykinin NK-2 receptor.

Fedi V, Altamura M, Balacco G, Canfarini F, Criscuoli M, Giannotti D, Giolitti A, Giuliani S, Guidi A, Harmat NJ, Nannicini R, Pasqui F, Patacchini R, Perrotta E, Tramontana M, Triolo A, Maggi CA. Fedi V, et al. Among authors: harmat nj. J Med Chem. 2004 Dec 30;47(27):6935-47. doi: 10.1021/jm040832y. J Med Chem. 2004. PMID: 15615542

4

Modulation on C- and N-terminal moieties of a series of potent and selective linear tachykinin NK(2) receptor antagonists.

Gensini M, Altamura M, Dimoulas T, Fedi V, Giannotti D, Giuliani S, Guidi A, Harmat NJ, Meini S, Nannicini R, Pasqui F, Tramontana M, Triolo A, Maggi CA. Gensini M, et al. Among authors: harmat nj. ChemMedChem. 2010 Jan;5(1):65-78. doi: 10.1002/cmdc.200900389. ChemMedChem. 2010. PMID: 19957262

5

Discovery of potent cyclic pseudopeptide human tachykinin NK-2 receptor antagonists.

Giannotti D, Perrotta E, Di Bugno C, Nannicini R, Harmat NJ, Giolitti A, Patacchini R, Renzetti AR, Rotondaro L, Giuliani S, Altamura M, Maggi CA. Giannotti D, et al. Among authors: harmat nj. J Med Chem. 2000 Nov 2;43(22):4041-4. doi: 10.1021/jm0010217. J Med Chem. 2000. PMID: 11063600 No abstract available.

6

In vitro and in vivo activity of analogues of the kinin B2 receptor antagonist MEN1 1270.

Meini S, Lecci A, Carini F, Tramontana M, Giuliani S, Maggi CA, Ricci R, Fabbri G, Anichini B, Harmat N, Rizzi A, Camarda V, Regoli D, Quartara L. Meini S, et al. Can J Physiol Pharmacol. 2002 Apr;80(4):293-302. doi: 10.1139/y02-022. Can J Physiol Pharmacol. 2002. PMID: 12025964

7

2,6-Diketopiperazines from amino acids, from solution-phase to solid-phase organic synthesis.

Perrotta E, Altamura M, Barani T, Bindi S, Giannotti D, Harmat NJ, Nannicini R, Maggi CA. Perrotta E, et al. Among authors: harmat nj. J Comb Chem. 2001 Sep-Oct;3(5):453-60. doi: 10.1021/cc0000904. J Comb Chem. 2001. PMID: 11549363

8

1,2-disubstituted cyclohexane derived tripeptide aldehydes as novel selective thrombin inhibitors.

Harmat NJ, Di Bugno C, Criscuoli M, Giorgi R, Lippi A, Martinelli A, Monti S, Subissi A. Harmat NJ, et al. Bioorg Med Chem Lett. 1998 May 19;8(10):1249-54. doi: 10.1016/s0960-894x(98)00200-5. Bioorg Med Chem Lett. 1998. PMID: 9871744

9

4-Diazinyl- and 4-pyridinylimidazoles: potent angiotensin II antagonists. A study of their activity and computational characterization.

Harmat NJ, Giorgi R, Bonaccorsi F, Cerbai G, Colombani SM, Renzetti AR, Cirillo R, Subissi A, Alagona G, Ghio C, et al. Harmat NJ, et al. J Med Chem. 1995 Jul 21;38(15):2925-37. doi: 10.1021/jm00015a015. J Med Chem. 1995. PMID: 7636853

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