Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 2
2003 3
2004 8
2005 10
2006 9
2007 9
2008 9
2009 5
2010 1
2011 5
2012 6
2013 5
2014 5
2015 12
2016 8
2017 12
2018 7
2019 9
2020 10
2021 7
2022 10
2023 6
2024 3

Text availability

Article attribute

Article type

Publication date

Search Results

147 results

Results by year

Filters applied: . Clear all
Page 1
Showing results for harry sirna
Your search for Harry Zirna retrieved no results
Proteome-wide mapping of short-lived proteins in human cells.
Li J, Cai Z, Vaites LP, Shen N, Mitchell DC, Huttlin EL, Paulo JA, Harry BL, Gygi SP. Li J, et al. Mol Cell. 2021 Nov 18;81(22):4722-4735.e5. doi: 10.1016/j.molcel.2021.09.015. Epub 2021 Oct 8. Mol Cell. 2021. PMID: 34626566 Free PMC article.
siRNA Therapeutics for the Therapy of COVID-19 and Other Coronaviruses.
Sajid MI, Moazzam M, Cho Y, Kato S, Xu A, Way JJ, Lohan S, Tiwari RK. Sajid MI, et al. Mol Pharm. 2021 Jun 7;18(6):2105-2121. doi: 10.1021/acs.molpharmaceut.0c01239. Epub 2021 May 4. Mol Pharm. 2021. PMID: 33945284 Review.
The U.S. Food and Drug Administration has recently approved three siRNA products for human use that garner significant hope in siRNA therapeutics for coronaviruses. ...Numerous successful in vitro studies and several investigations to address the clinical applicatio …
The U.S. Food and Drug Administration has recently approved three siRNA products for human use that garner significant hope in siR …
siRNA drug delivery across the blood-brain barrier in Alzheimer's disease.
Imran Sajid M, Sultan Sheikh F, Anis F, Nasim N, Sumbria RK, Nauli SM, Kumar Tiwari R. Imran Sajid M, et al. Adv Drug Deliv Rev. 2023 Aug;199:114968. doi: 10.1016/j.addr.2023.114968. Epub 2023 Jun 21. Adv Drug Deliv Rev. 2023. PMID: 37353152 Review.
The advancements in understanding the causative genes and non-coding sequences at the molecular level of the pathophysiology of AD have resulted in several exciting research papers that employed small interfering RNA (siRNA)-based therapy. Although …
The advancements in understanding the causative genes and non-coding sequences at the molecular level of the pathophysiology of AD have resu …
Overcoming Barriers for siRNA Therapeutics: From Bench to Bedside.
Sajid MI, Moazzam M, Kato S, Yeseom Cho K, Tiwari RK. Sajid MI, et al. Pharmaceuticals (Basel). 2020 Oct 7;13(10):294. doi: 10.3390/ph13100294. Pharmaceuticals (Basel). 2020. PMID: 33036435 Free PMC article. Review.
Small interfering RNA (siRNA) can efficiently trigger RNAi silencing of specific genes. FDA Approval of siRNA therapeutics in recent years garnered a new hope in siRNA therapeutics. ...
Small interfering RNA (siRNA) can efficiently trigger RNAi silencing of specific genes. FDA Approval of siRNA …
Amphiphilic Peptides for Efficient siRNA Delivery.
Mozaffari S, Bousoik E, Amirrad F, Lamboy R, Coyle M, Hall R, Alasmari A, Mahdipoor P, Parang K, Montazeri Aliabadi H. Mozaffari S, et al. Polymers (Basel). 2019 Apr 17;11(4):703. doi: 10.3390/polym11040703. Polymers (Basel). 2019. PMID: 30999603 Free PMC article.
The data also showed that co-formulation of [WR](5) with lipid DOPE significantly enhanced the efficiency of siRNA delivery by up to ~2-fold compared to peptide alone. Based on the data indicating the efficiency of [WR](5) in siRNA delivery, peptides containing argi …
The data also showed that co-formulation of [WR](5) with lipid DOPE significantly enhanced the efficiency of siRNA delivery by up to …
Cyclic Peptide-Gadolinium Nanocomplexes as siRNA Delivery Tools.
Nasrolahi Shirazi A, Sajid MI, Mandal D, Stickley D, Nagasawa S, Long J, Lohan S, Parang K, Tiwari RK. Nasrolahi Shirazi A, et al. Pharmaceuticals (Basel). 2021 Oct 20;14(11):1064. doi: 10.3390/ph14111064. Pharmaceuticals (Basel). 2021. PMID: 34832846 Free PMC article.
Fluorescence-activated cell sorting (FACS) analysis indicated that the cellular uptakes of Alexa-488-labeled siRNA were found to be enhanced by more than 10 folds in the presence of [(WR)(5)C]-GdNPs compared with siRNA alone in CCRF-CEM and MDA-MB-231 cells after 6 …
Fluorescence-activated cell sorting (FACS) analysis indicated that the cellular uptakes of Alexa-488-labeled siRNA were found to be e …
Redox-Responsive Disulfide Cyclic Peptides: A New Strategy for siRNA Delivery.
Mandal D, Mohammed EHM, Lohan S, Mandipoor P, Baradaran D, Tiwari RK, Parang K, Aliabadi HM. Mandal D, et al. Mol Pharm. 2022 May 2;19(5):1338-1355. doi: 10.1021/acs.molpharmaceut.1c00879. Epub 2022 Mar 29. Mol Pharm. 2022. PMID: 35347995
RNA interference (RNAi) is a powerful tool capable of targeting virtually any protein without time-consuming and expensive drug development studies. ...Our hypothesis was that peptide structures would undergo reduction by intracellular glutathione (more abundant in cancer …
RNA interference (RNAi) is a powerful tool capable of targeting virtually any protein without time-consuming and expensive drug devel …
Nanocarrier mediated delivery of siRNA/miRNA in combination with chemotherapeutic agents for cancer therapy: current progress and advances.
Gandhi NS, Tekade RK, Chougule MB. Gandhi NS, et al. J Control Release. 2014 Nov 28;194:238-56. doi: 10.1016/j.jconrel.2014.09.001. Epub 2014 Sep 7. J Control Release. 2014. PMID: 25204288 Free PMC article. Review.
Especially small interfering RNA (siRNA) and micro RNA (miRNA), are able to knock down the carcinogenic genes by targeting the mRNA expression, which underlies the uniqueness of this therapeutic approach. ...The objective of this article is to r …
Especially small interfering RNA (siRNA) and micro RNA (miRNA), are able to knock down the carcinogenic g …
Prospects for RNAi Therapy of COVID-19.
Uludağ H, Parent K, Aliabadi HM, Haddadi A. Uludağ H, et al. Front Bioeng Biotechnol. 2020 Jul 30;8:916. doi: 10.3389/fbioe.2020.00916. eCollection 2020. Front Bioeng Biotechnol. 2020. PMID: 32850752 Free PMC article. Review.
There were no drug treatments or vaccines approved for SARS-CoV-2 at the onset of pandemic, necessitating an urgent need to develop effective therapeutics. To this end, the innate RNA interference (RNAi) mechanism can be employed to develop front line therapies against the …
There were no drug treatments or vaccines approved for SARS-CoV-2 at the onset of pandemic, necessitating an urgent need to develop effectiv …
Oleyl Conjugated Histidine-Arginine Cell-Penetrating Peptides as Promising Agents for siRNA Delivery.
Sajid MI, Mandal D, El-Sayed NS, Lohan S, Moreno J, Tiwari RK. Sajid MI, et al. Pharmaceutics. 2022 Apr 18;14(4):881. doi: 10.3390/pharmaceutics14040881. Pharmaceutics. 2022. PMID: 35456715 Free PMC article.
Recent approvals of siRNA-based products motivated the scientific community to explore siRNA as a treatment option for several intractable ailments, especially cancer. ...Herein, we report a series of oleyl conjugated histidine-arginine peptides as a promising nonvi …
Recent approvals of siRNA-based products motivated the scientific community to explore siRNA as a treatment option for several …
147 results