Hartleben B - Search Results

1

Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity.

Hartleben B, Schweizer H, Lübben P, Bartram MP, Möller CC, Herr R, Wei C, Neumann-Haefelin E, Schermer B, Zentgraf H, Kerjaschki D, Reiser J, Walz G, Benzing T, Huber TB. Hartleben B, et al. J Biol Chem. 2008 Aug 22;283(34):23033-8. doi: 10.1074/jbc.M803143200. Epub 2008 Jun 18. J Biol Chem. 2008. PMID: 18562307 Free PMC article.

2

The carboxyl terminus of Neph family members binds to the PDZ domain protein zonula occludens-1.

Huber TB, Schmidts M, Gerke P, Schermer B, Zahn A, Hartleben B, Sellin L, Walz G, Benzing T. Huber TB, et al. Among authors: hartleben b. J Biol Chem. 2003 Apr 11;278(15):13417-21. doi: 10.1074/jbc.C200678200. Epub 2003 Feb 10. J Biol Chem. 2003. PMID: 12578837 Free article.

3

Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling.

Huber TB, Hartleben B, Kim J, Schmidts M, Schermer B, Keil A, Egger L, Lecha RL, Borner C, Pavenstädt H, Shaw AS, Walz G, Benzing T. Huber TB, et al. Among authors: hartleben b. Mol Cell Biol. 2003 Jul;23(14):4917-28. doi: 10.1128/MCB.23.14.4917-4928.2003. Mol Cell Biol. 2003. PMID: 12832477 Free PMC article.

4

Loss of podocyte aPKClambda/iota causes polarity defects and nephrotic syndrome.

Huber TB, Hartleben B, Winkelmann K, Schneider L, Becker JU, Leitges M, Walz G, Haller H, Schiffer M. Huber TB, et al. Among authors: hartleben b. J Am Soc Nephrol. 2009 Apr;20(4):798-806. doi: 10.1681/ASN.2008080871. Epub 2009 Mar 11. J Am Soc Nephrol. 2009. PMID: 19279126 Free PMC article.

5

Podocyte polarity signalling.

Simons M, Hartleben B, Huber TB. Simons M, et al. Among authors: hartleben b. Curr Opin Nephrol Hypertens. 2009 Jul;18(4):324-30. doi: 10.1097/MNH.0b013e32832e316d. Curr Opin Nephrol Hypertens. 2009. PMID: 19542980 Review.

6

Role of the polarity protein Scribble for podocyte differentiation and maintenance.

Hartleben B, Widmeier E, Wanner N, Schmidts M, Kim ST, Schneider L, Mayer B, Kerjaschki D, Miner JH, Walz G, Huber TB. Hartleben B, et al. PLoS One. 2012;7(5):e36705. doi: 10.1371/journal.pone.0036705. Epub 2012 May 7. PLoS One. 2012. PMID: 22586490 Free PMC article.

7

aPKCλ/ι and aPKCζ contribute to podocyte differentiation and glomerular maturation.

Hartleben B, Widmeier E, Suhm M, Worthmann K, Schell C, Helmstädter M, Wiech T, Walz G, Leitges M, Schiffer M, Huber TB. Hartleben B, et al. J Am Soc Nephrol. 2013 Feb;24(2):253-67. doi: 10.1681/ASN.2012060582. Epub 2013 Jan 18. J Am Soc Nephrol. 2013. PMID: 23334392 Free PMC article.

8

Molecular basis of the functional podocin-nephrin complex: mutations in the NPHS2 gene disrupt nephrin targeting to lipid raft microdomains.

Huber TB, Simons M, Hartleben B, Sernetz L, Schmidts M, Gundlach E, Saleem MA, Walz G, Benzing T. Huber TB, et al. Among authors: hartleben b. Hum Mol Genet. 2003 Dec 15;12(24):3397-405. doi: 10.1093/hmg/ddg360. Epub 2003 Oct 21. Hum Mol Genet. 2003. PMID: 14570703

9

Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice.

Hartleben B, Gödel M, Meyer-Schwesinger C, Liu S, Ulrich T, Köbler S, Wiech T, Grahammer F, Arnold SJ, Lindenmeyer MT, Cohen CD, Pavenstädt H, Kerjaschki D, Mizushima N, Shaw AS, Walz G, Huber TB. Hartleben B, et al. J Clin Invest. 2010 Apr;120(4):1084-96. doi: 10.1172/JCI39492. J Clin Invest. 2010. PMID: 20200449 Free PMC article.

10

A model organism approach: defining the role of Neph proteins as regulators of neuron and kidney morphogenesis.

Neumann-Haefelin E, Kramer-Zucker A, Slanchev K, Hartleben B, Noutsou F, Martin K, Wanner N, Ritter A, Gödel M, Pagel P, Fu X, Müller A, Baumeister R, Walz G, Huber TB. Neumann-Haefelin E, et al. Among authors: hartleben b. Hum Mol Genet. 2010 Jun 15;19(12):2347-59. doi: 10.1093/hmg/ddq108. Epub 2010 Mar 16. Hum Mol Genet. 2010. PMID: 20233749

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