Hartley JA - Search Results

1

Benzoyl and cinnamoyl nitrogen mustard derivatives of benzoheterocyclic analogues of the tallimustine: synthesis and antitumour activity.

Baraldi PG, Romagnoli R, Giovanna Pavani M, del Carmen Nunez M, Bingham JP, Hartley JA. Baraldi PG, et al. Among authors: hartley ja. Bioorg Med Chem. 2002 May;10(5):1611-8. doi: 10.1016/s0968-0896(01)00425-4. Bioorg Med Chem. 2002. PMID: 11886822

2

DNA sequence selectivity of guanine-N7 alkylation by nitrogen mustards is preserved in intact cells.

Hartley JA, Bingham JP, Souhami RL. Hartley JA, et al. Nucleic Acids Res. 1992 Jun 25;20(12):3175-8. doi: 10.1093/nar/20.12.3175. Nucleic Acids Res. 1992. PMID: 1620613 Free PMC article.

3

Targeting of tumor cells and DNA by a chlorambucil-spermidine conjugate.

Holley JL, Mather A, Wheelhouse RT, Cullis PM, Hartley JA, Bingham JP, Cohen GM. Holley JL, et al. Among authors: hartley ja. Cancer Res. 1992 Aug 1;52(15):4190-5. Cancer Res. 1992. PMID: 1638533

4

DNA damage by anticancer agents and its repair: mapping in cells at the subgene level with quantitative polymerase chain reaction.

Grimaldi KA, Bingham JP, Souhami RL, Hartley JA. Grimaldi KA, et al. Among authors: hartley ja. Anal Biochem. 1994 Oct;222(1):236-42. doi: 10.1006/abio.1994.1479. Anal Biochem. 1994. PMID: 7856855

5

DNA sequence-specific adenine alkylation by the novel antitumor drug tallimustine (FCE 24517), a benzoyl nitrogen mustard derivative of distamycin.

Broggini M, Coley HM, Mongelli N, Pesenti E, Wyatt MD, Hartley JA, D'Incalci M. Broggini M, et al. Among authors: hartley ja. Nucleic Acids Res. 1995 Jan 11;23(1):81-7. doi: 10.1093/nar/23.1.81. Nucleic Acids Res. 1995. PMID: 7870593 Free PMC article.

6

Strand-specific measurement of cisplatin-induced DNA damage and repair using quantitative PCR.

Bingham JP, Hartley JA, Souhami RL, Grimaldi KA. Bingham JP, et al. Among authors: hartley ja. Nucleic Acids Res. 1996 Mar 1;24(5):987-9. doi: 10.1093/nar/24.5.987. Nucleic Acids Res. 1996. PMID: 8600473 Free PMC article. No abstract available.

7

Structure-activity relationship of a series of C-terminus modified aminoalkyl, diaminoalkyl- and anilino-containing analogues of the benzoic acid mustard distamycin derivative tallimustine: synthesis, DNA binding and cytotoxicity studies.

Brooks N, Hartley JA, Simpson JE Jr, Wright SR, Woo S, Centioni S, Fontaine MD, McIntyre TE, Lee M. Brooks N, et al. Among authors: hartley ja. Bioorg Med Chem. 1997 Aug;5(8):1497-507. doi: 10.1016/s0968-0896(97)00096-5. Bioorg Med Chem. 1997. PMID: 9313856

8

PCR-based assays for strand-specific measurement of DNA damage and repair. I. Strand-specific quantitative PCR.

Grimaldi KA, Bingham JP, Hartley JA. Grimaldi KA, et al. Among authors: hartley ja. Methods Mol Biol. 1999;113:227-40. doi: 10.1385/1-59259-675-4:227. Methods Mol Biol. 1999. PMID: 10443424 No abstract available.

9

Novel furano analogues of duocarmycin C1 and C2: design, synthesis, and biological evaluation of seco-iso-cyclopropylfurano[2,3-e]indoline (seco-iso-CFI) and seco-cyclopropyltetrahydrofurano[2,3-f]quinoline (seco-CFQ) analogues.

Howard TT, Lingerfelt BM, Purnell BL, Scott AE, Price CA, Townes HM, McNulty L, Handl HL, Summerville K, Hudson SJ, Bowen JP, Kiakos K, Hartley JA, Lee M. Howard TT, et al. Among authors: hartley ja. Bioorg Med Chem. 2002 Sep;10(9):2941-52. doi: 10.1016/s0968-0896(02)00157-8. Bioorg Med Chem. 2002. PMID: 12110316

10

Design, synthesis, and biological activity of hybrid compounds between uramustine and DNA minor groove binder distamycin A.

Baraldi PG, Romagnoli R, Guadix AE, Pineda de las Infantas MJ, Gallo MA, Espinosa A, Martinez A, Bingham JP, Hartley JA. Baraldi PG, et al. Among authors: hartley ja. J Med Chem. 2002 Aug 15;45(17):3630-8. doi: 10.1021/jm011113b. J Med Chem. 2002. PMID: 12166936

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