Hartmann G - Search Results

1

Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase.

Gao P, Ascano M, Wu Y, Barchet W, Gaffney BL, Zillinger T, Serganov AA, Liu Y, Jones RA, Hartmann G, Tuschl T, Patel DJ. Gao P, et al. Among authors: hartmann g. Cell. 2013 May 23;153(5):1094-107. doi: 10.1016/j.cell.2013.04.046. Epub 2013 May 3. Cell. 2013. PMID: 23647843 Free PMC article.

2

A mammalian microRNA expression atlas based on small RNA library sequencing.

Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foà R, Schliwka J, Fuchs U, Novosel A, Müller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M, Weir DB, Choksi R, De Vita G, Frezzetti D, Trompeter HI, Hornung V, Teng G, Hartmann G, Palkovits M, Di Lauro R, Wernet P, Macino G, Rogler CE, Nagle JW, Ju J, Papavasiliou FN, Benzing T, Lichter P, Tam W, Brownstein MJ, Bosio A, Borkhardt A, Russo JJ, Sander C, Zavolan M, Tuschl T. Landgraf P, et al. Among authors: hartmann g. Cell. 2007 Jun 29;129(7):1401-14. doi: 10.1016/j.cell.2007.04.040. Cell. 2007. PMID: 17604727 Free PMC article.

3

Structural and functional insights into 5'-ppp RNA pattern recognition by the innate immune receptor RIG-I.

Wang Y, Ludwig J, Schuberth C, Goldeck M, Schlee M, Li H, Juranek S, Sheng G, Micura R, Tuschl T, Hartmann G, Patel DJ. Wang Y, et al. Among authors: hartmann g. Nat Struct Mol Biol. 2010 Jul;17(7):781-7. doi: 10.1038/nsmb.1863. Epub 2010 Jun 27. Nat Struct Mol Biol. 2010. PMID: 20581823 Free PMC article.

4

Monocyte-mediated inhibition of TLR9-dependent IFN-α induction in plasmacytoid dendritic cells questions bacterial DNA as the active ingredient of bacterial lysates.

Poth JM, Coch C, Busch N, Boehm O, Schlee M, Janke M, Zillinger T, Schildgen O, Barchet W, Hartmann G. Poth JM, et al. Among authors: hartmann g. J Immunol. 2010 Dec 15;185(12):7367-73. doi: 10.4049/jimmunol.1001798. Epub 2010 Nov 5. J Immunol. 2010. PMID: 21057083

5

Nucleic acid adjuvants: toward an educated vaccine.

van den Boorn JG, Barchet W, Hartmann G. van den Boorn JG, et al. Among authors: hartmann g. Adv Immunol. 2012;114:1-32. doi: 10.1016/B978-0-12-396548-6.00001-9. Adv Immunol. 2012. PMID: 22449776 Review.

6

RIG-I detects triphosphorylated RNA of Listeria monocytogenes during infection in non-immune cells.

Hagmann CA, Herzner AM, Abdullah Z, Zillinger T, Jakobs C, Schuberth C, Coch C, Higgins PG, Wisplinghoff H, Barchet W, Hornung V, Hartmann G, Schlee M. Hagmann CA, et al. Among authors: hartmann g. PLoS One. 2013 Apr 30;8(4):e62872. doi: 10.1371/journal.pone.0062872. Print 2013. PLoS One. 2013. PMID: 23653683 Free PMC article.

7

Structure-function analysis of STING activation by c[G(2',5')pA(3',5')p] and targeting by antiviral DMXAA.

Gao P, Ascano M, Zillinger T, Wang W, Dai P, Serganov AA, Gaffney BL, Shuman S, Jones RA, Deng L, Hartmann G, Barchet W, Tuschl T, Patel DJ. Gao P, et al. Among authors: hartmann g. Cell. 2013 Aug 15;154(4):748-62. doi: 10.1016/j.cell.2013.07.023. Epub 2013 Aug 1. Cell. 2013. PMID: 23910378 Free PMC article.

8

Oxidative damage of DNA confers resistance to cytosolic nuclease TREX1 degradation and potentiates STING-dependent immune sensing.

Gehrke N, Mertens C, Zillinger T, Wenzel J, Bald T, Zahn S, Tüting T, Hartmann G, Barchet W. Gehrke N, et al. Among authors: hartmann g. Immunity. 2013 Sep 19;39(3):482-95. doi: 10.1016/j.immuni.2013.08.004. Epub 2013 Aug 29. Immunity. 2013. PMID: 23993650 Free article.

9

Binding-pocket and lid-region substitutions render human STING sensitive to the species-specific drug DMXAA.

Gao P, Zillinger T, Wang W, Ascano M, Dai P, Hartmann G, Tuschl T, Deng L, Barchet W, Patel DJ. Gao P, et al. Among authors: hartmann g. Cell Rep. 2014 Sep 25;8(6):1668-1676. doi: 10.1016/j.celrep.2014.08.010. Epub 2014 Sep 4. Cell Rep. 2014. PMID: 25199835 Free PMC article.

10

Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA.

Herzner AM, Hagmann CA, Goldeck M, Wolter S, Kübler K, Wittmann S, Gramberg T, Andreeva L, Hopfner KP, Mertens C, Zillinger T, Jin T, Xiao TS, Bartok E, Coch C, Ackermann D, Hornung V, Ludwig J, Barchet W, Hartmann G, Schlee M. Herzner AM, et al. Among authors: hartmann g. Nat Immunol. 2015 Oct;16(10):1025-33. doi: 10.1038/ni.3267. Epub 2015 Sep 7. Nat Immunol. 2015. PMID: 26343537 Free PMC article.

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