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M01 as a novel drug enhancer for specifically targeting the blood-brain barrier.
Breitkreuz-Korff O, Tscheik C, Del Vecchio G, Dithmer S, Walther W, Orthmann A, Wolburg H, Haseloff RF, Schröder L, Blasig IE, Winkler L. Breitkreuz-Korff O, et al. Among authors: haseloff rf. J Control Release. 2021 Oct 10;338:137-148. doi: 10.1016/j.jconrel.2021.08.014. Epub 2021 Aug 10. J Control Release. 2021. PMID: 34384796 Free article.
Tight junction proteins at the blood-brain barrier: far more than claudin-5.
Berndt P, Winkler L, Cording J, Breitkreuz-Korff O, Rex A, Dithmer S, Rausch V, Blasig R, Richter M, Sporbert A, Wolburg H, Blasig IE, Haseloff RF. Berndt P, et al. Among authors: haseloff rf. Cell Mol Life Sci. 2019 May;76(10):1987-2002. doi: 10.1007/s00018-019-03030-7. Epub 2019 Feb 7. Cell Mol Life Sci. 2019. PMID: 30734065
Tight junctions in the blood-brain barrier promote edema formation and infarct size in stroke - Ambivalent effects of sealing proteins.
Winkler L, Blasig R, Breitkreuz-Korff O, Berndt P, Dithmer S, Helms HC, Puchkov D, Devraj K, Kaya M, Qin Z, Liebner S, Wolburg H, Andjelkovic AV, Rex A, Blasig IE, Haseloff RF. Winkler L, et al. Among authors: haseloff rf. J Cereb Blood Flow Metab. 2021 Jan;41(1):132-145. doi: 10.1177/0271678X20904687. Epub 2020 Feb 13. J Cereb Blood Flow Metab. 2021. PMID: 32054373 Free PMC article.
Structure and function of claudins.
Krause G, Winkler L, Mueller SL, Haseloff RF, Piontek J, Blasig IE. Krause G, et al. Among authors: haseloff rf. Biochim Biophys Acta. 2008 Mar;1778(3):631-45. doi: 10.1016/j.bbamem.2007.10.018. Epub 2007 Oct 25. Biochim Biophys Acta. 2008. PMID: 18036336 Free article. Review.
Occludin protein family: oxidative stress and reducing conditions.
Blasig IE, Bellmann C, Cording J, Del Vecchio G, Zwanziger D, Huber O, Haseloff RF. Blasig IE, et al. Among authors: haseloff rf. Antioxid Redox Signal. 2011 Sep 1;15(5):1195-219. doi: 10.1089/ars.2010.3542. Epub 2011 May 5. Antioxid Redox Signal. 2011. PMID: 21235353 Review.
Redox Regulation of Cell Contacts by Tricellulin and Occludin: Redox-Sensitive Cysteine Sites in Tricellulin Regulate Both Tri- and Bicellular Junctions in Tissue Barriers as Shown in Hypoxia and Ischemia.
Cording J, Günther R, Vigolo E, Tscheik C, Winkler L, Schlattner I, Lorenz D, Haseloff RF, Schmidt-Ott KM, Wolburg H, Blasig IE. Cording J, et al. Among authors: haseloff rf. Antioxid Redox Signal. 2015 Nov 1;23(13):1035-49. doi: 10.1089/ars.2014.6162. Epub 2015 Jun 8. Antioxid Redox Signal. 2015. PMID: 25919114
Claudin peptidomimetics modulate tissue barriers for enhanced drug delivery.
Dithmer S, Staat C, Müller C, Ku MC, Pohlmann A, Niendorf T, Gehne N, Fallier-Becker P, Kittel Á, Walter FR, Veszelka S, Deli MA, Blasig R, Haseloff RF, Blasig IE, Winkler L. Dithmer S, et al. Among authors: haseloff rf. Ann N Y Acad Sci. 2017 Jun;1397(1):169-184. doi: 10.1111/nyas.13359. Epub 2017 May 15. Ann N Y Acad Sci. 2017. PMID: 28505395
Trictide, a tricellulin-derived peptide to overcome cellular barriers.
Cording J, Arslan B, Staat C, Dithmer S, Krug SM, Krüger A, Berndt P, Günther R, Winkler L, Blasig IE, Haseloff RF. Cording J, et al. Among authors: haseloff rf. Ann N Y Acad Sci. 2017 Oct;1405(1):89-101. doi: 10.1111/nyas.13392. Epub 2017 Jun 20. Ann N Y Acad Sci. 2017. PMID: 28633193
52 results