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Pharmacogenomics of GPCR Drug Targets.
Hauser AS, Chavali S, Masuho I, Jahn LJ, Martemyanov KA, Gloriam DE, Babu MM. Hauser AS, et al. Cell. 2018 Jan 11;172(1-2):41-54.e19. doi: 10.1016/j.cell.2017.11.033. Epub 2017 Dec 14. Cell. 2018. PMID: 29249361 Free PMC article.
GPCRdb: an information system for G protein-coupled receptors.
Isberg V, Mordalski S, Munk C, Rataj K, Harpsøe K, Hauser AS, Vroling B, Bojarski AJ, Vriend G, Gloriam DE. Isberg V, et al. Among authors: hauser as. Nucleic Acids Res. 2016 Jan 4;44(D1):D356-64. doi: 10.1093/nar/gkv1178. Epub 2015 Nov 17. Nucleic Acids Res. 2016. PMID: 26582914 Free PMC article.
GPCRdb: the G protein-coupled receptor database - an introduction.
Munk C, Isberg V, Mordalski S, Harpsøe K, Rataj K, Hauser AS, Kolb P, Bojarski AJ, Vriend G, Gloriam DE. Munk C, et al. Among authors: hauser as. Br J Pharmacol. 2016 Jul;173(14):2195-207. doi: 10.1111/bph.13509. Epub 2016 Jun 3. Br J Pharmacol. 2016. PMID: 27155948 Free PMC article. Review.
The orphan G protein-coupled receptor GPR139 is activated by the peptides: Adrenocorticotropic hormone (ACTH), α-, and β-melanocyte stimulating hormone (α-MSH, and β-MSH), and the conserved core motif HFRW.
Nøhr AC, Shehata MA, Hauser AS, Isberg V, Mokrosinski J, Andersen KB, Farooqi IS, Pedersen DS, Gloriam DE, Bräuner-Osborne H. Nøhr AC, et al. Among authors: hauser as. Neurochem Int. 2017 Jan;102:105-113. doi: 10.1016/j.neuint.2016.11.012. Epub 2016 Dec 1. Neurochem Int. 2017. PMID: 27916541 Free PMC article.
GPCRdb: an information system for G protein-coupled receptors.
Isberg V, Mordalski S, Munk C, Rataj K, Harpsøe K, Hauser AS, Vroling B, Bojarski AJ, Vriend G, Gloriam DE. Isberg V, et al. Among authors: hauser as. Nucleic Acids Res. 2017 Mar 17;45(5):2936. doi: 10.1093/nar/gkw1218. Nucleic Acids Res. 2017. PMID: 27923934 Free PMC article. No abstract available.
Selectivity determinants of GPCR-G-protein binding.
Flock T, Hauser AS, Lund N, Gloriam DE, Balaji S, Babu MM. Flock T, et al. Among authors: hauser as. Nature. 2017 May 18;545(7654):317-322. doi: 10.1038/nature22070. Epub 2017 May 10. Nature. 2017. PMID: 28489817 Free PMC article.
Trends in GPCR drug discovery: new agents, targets and indications.
Hauser AS, Attwood MM, Rask-Andersen M, Schiöth HB, Gloriam DE. Hauser AS, et al. Nat Rev Drug Discov. 2017 Dec;16(12):829-842. doi: 10.1038/nrd.2017.178. Epub 2017 Oct 27. Nat Rev Drug Discov. 2017. PMID: 29075003 Free PMC article. Review.
34 results