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Intra-arterial administration of tumor-targeting Salmonella typhimurium A1-R regresses a cisplatin-resistant relapsed osteosarcoma in a patient-derived orthotopic xenograft (PDOX) mouse model.
Igarashi K, Kawaguchi K, Murakami T, Kiyuna T, Miyake K, Nelson SD, Dry SM, Li Y, Yanagawa J, Russell TA, Singh AS, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Eilber FC, Hoffman RM. Igarashi K, et al. Among authors: hayashi k. Cell Cycle. 2017 Jun 18;16(12):1164-1170. doi: 10.1080/15384101.2017.1317417. Epub 2017 May 11. Cell Cycle. 2017. PMID: 28494180 Free PMC article.
Temozolomide combined with irinotecan caused regression in an adult pleomorphic rhabdomyosarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model.
Igarashi K, Kawaguchi K, Kiyuna T, Murakami T, Miwa S, Nelson SD, Dry SM, Li Y, Singh AS, Kimura H, Hayashi K, Yamamoto N, Tsuchiya H, Eilber FC, Hoffman RM. Igarashi K, et al. Among authors: hayashi k. Oncotarget. 2017 Mar 24;8(44):75874-75880. doi: 10.18632/oncotarget.16548. eCollection 2017 Sep 29. Oncotarget. 2017. PMID: 29100276 Free PMC article.
Growth of doxorubicin-resistant undifferentiated spindle-cell sarcoma PDOX is arrested by metabolic targeting with recombinant methioninase.
Igarashi K, Li S, Han Q, Tan Y, Kawaguchi K, Murakami T, Kiyuna T, Miyake K, Li Y, Nelson SD, Dry SM, Singh AS, Elliott IA, Russell TA, Eckardt MA, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Eilber FC, Hoffman RM. Igarashi K, et al. Among authors: hayashi k. J Cell Biochem. 2018 Apr;119(4):3537-3544. doi: 10.1002/jcb.26527. Epub 2018 Jan 2. J Cell Biochem. 2018. PMID: 29143983
Recombinant methioninase in combination with doxorubicin (DOX) overcomes first-line DOX resistance in a patient-derived orthotopic xenograft nude-mouse model of undifferentiated spindle-cell sarcoma.
Igarashi K, Kawaguchi K, Li S, Han Q, Tan Y, Murakami T, Kiyuna T, Miyake K, Miyake M, Singh AS, Eckardt MA, Nelson SD, Russell TA, Dry SM, Li Y, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Singh SR, Eilber FC, Hoffman RM. Igarashi K, et al. Among authors: hayashi k. Cancer Lett. 2018 Mar 28;417:168-173. doi: 10.1016/j.canlet.2017.12.028. Epub 2018 Jan 3. Cancer Lett. 2018. PMID: 29306021
Tumor-targeting Salmonella typhimurium A1-R is a highly effective general therapeutic for undifferentiated soft tissue sarcoma patient-derived orthotopic xenograft nude-mouse models.
Igarashi K, Kawaguchi K, Kiyuna T, Miyake K, Miyake M, Singh AS, Eckardt MA, Nelson SD, Russell TA, Dry SM, Li Y, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Singh SR, Eilber FC, Hoffman RM. Igarashi K, et al. Among authors: hayashi k. Biochem Biophys Res Commun. 2018 Mar 18;497(4):1055-1061. doi: 10.1016/j.bbrc.2018.02.174. Epub 2018 Feb 23. Biochem Biophys Res Commun. 2018. PMID: 29481803
Temozolomide combined with irinotecan regresses a cisplatinum-resistant relapsed osteosarcoma in a patient-derived orthotopic xenograft (PDOX) precision-oncology mouse model.
Igarashi K, Kawaguchi K, Kiyuna T, Miyake K, Miyake M, Li Y, Nelson SD, Dry SM, Singh AS, Elliott IA, Russell TA, Eckardt MA, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Eilber FC, Hoffman RM. Igarashi K, et al. Among authors: hayashi k. Oncotarget. 2017 Dec 4;9(8):7774-7781. doi: 10.18632/oncotarget.22892. eCollection 2018 Jan 30. Oncotarget. 2017. PMID: 29487690 Free PMC article.
8,444 results