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Huntingtin is required for normal hematopoiesis.
Metzler M, Helgason CD, Dragatsis I, Zhang T, Gan L, Pineault N, Zeitlin SO, Humphries RK, Hayden MR. Metzler M, et al. Among authors: hayden mr. Hum Mol Genet. 2000 Feb 12;9(3):387-94. doi: 10.1093/hmg/9.3.387. Hum Mol Genet. 2000. PMID: 10655548
Life without huntingtin: normal differentiation into functional neurons.
Metzler M, Chen N, Helgason CD, Graham RK, Nichol K, McCutcheon K, Nasir J, Humphries RK, Raymond LA, Hayden MR. Metzler M, et al. Among authors: hayden mr. J Neurochem. 1999 Mar;72(3):1009-18. doi: 10.1046/j.1471-4159.1999.0721009.x. J Neurochem. 1999. PMID: 10037472 Free article.
Evidence for both the nucleus and cytoplasm as subcellular sites of pathogenesis in Huntington's disease in cell culture and in transgenic mice expressing mutant huntingtin.
Hackam AS, Hodgson JG, Singaraja R, Zhang T, Gan L, Gutekunst CA, Hersch SM, Hayden MR. Hackam AS, et al. Among authors: hayden mr. Philos Trans R Soc Lond B Biol Sci. 1999 Jun 29;354(1386):1047-55. doi: 10.1098/rstb.1999.0457. Philos Trans R Soc Lond B Biol Sci. 1999. PMID: 10434304 Free PMC article. Review.
891 results