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Pridopidine activates neuroprotective pathways impaired in Huntington Disease.
Geva M, Kusko R, Soares H, Fowler KD, Birnberg T, Barash S, -Wagner AM, Fine T, Lysaght A, Weiner B, Cha Y, Kolitz S, Towfic F, Orbach A, Laufer R, Zeskind B, Grossman I, Hayden MR. Geva M, et al. Among authors: hayden mr. Hum Mol Genet. 2016 Sep 15;25(18):3975-3987. doi: 10.1093/hmg/ddw238. Epub 2016 Jul 27. Hum Mol Genet. 2016. PMID: 27466197 Free PMC article.
Large-scale transcriptomic analysis reveals that pridopidine reverses aberrant gene expression and activates neuroprotective pathways in the YAC128 HD mouse.
Kusko R, Dreymann J, Ross J, Cha Y, Escalante-Chong R, Garcia-Miralles M, Tan LJ, Burczynski ME, Zeskind B, Laifenfeld D, Pouladi M, Geva M, Grossman I, Hayden MR. Kusko R, et al. Among authors: hayden mr. Mol Neurodegener. 2018 May 21;13(1):25. doi: 10.1186/s13024-018-0259-3. Mol Neurodegener. 2018. PMID: 29783994 Free PMC article.
Gene expression studies of a human monocyte cell line identify dissimilarities between differently manufactured glatiramoids.
Kolitz S, Hasson T, Towfic F, Funt JM, Bakshi S, Fowler KD, Laifenfeld D, Grinspan A, Artyomov MN, Birnberg T, Schwartz R, Komlosh A, Hayardeny L, Ladkani D, Hayden MR, Zeskind B, Grossman I. Kolitz S, et al. Among authors: hayden mr. Sci Rep. 2015 May 22;5:10191. doi: 10.1038/srep10191. Sci Rep. 2015. PMID: 25998228 Free PMC article.
Functional effects of the antigen glatiramer acetate are complex and tightly associated with its composition.
Hasson T, Kolitz S, Towfic F, Laifenfeld D, Bakshi S, Beriozkin O, Shacham-Abramson M, Timan B, Fowler KD, Birnberg T, Konya A, Komlosh A, Ladkani D, Hayden MR, Zeskind B, Grossman I. Hasson T, et al. Among authors: hayden mr. J Neuroimmunol. 2016 Jan 15;290:84-95. doi: 10.1016/j.jneuroim.2015.11.020. Epub 2015 Nov 24. J Neuroimmunol. 2016. PMID: 26711576 Free article.
Laquinimod arrests experimental autoimmune encephalomyelitis by activating the aryl hydrocarbon receptor.
Kaye J, Piryatinsky V, Birnberg T, Hingaly T, Raymond E, Kashi R, Amit-Romach E, Caballero IS, Towfic F, Ator MA, Rubinstein E, Laifenfeld D, Orbach A, Shinar D, Marantz Y, Grossman I, Knappertz V, Hayden MR, Laufer R. Kaye J, et al. Among authors: hayden mr. Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6145-E6152. doi: 10.1073/pnas.1607843113. Epub 2016 Sep 26. Proc Natl Acad Sci U S A. 2016. PMID: 27671624 Free PMC article.
891 results