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2010 1
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2020 2
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2023 1
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Exploring Genetic Associations of 3 Types of Risk Factors With Ischemic Stroke: An Integrated Bioinformatics Study.
Liu Y, Wang W, Cui X, Lyu J, Xie Y. Liu Y, et al. Stroke. 2024 Jun;55(6):1619-1628. doi: 10.1161/STROKEAHA.123.044424. Epub 2024 Apr 9. Stroke. 2024. PMID: 38591222
We identified 73 genes that are linked to blood pressure and circulating lipids in the context of IS, and 16 are differentially expressed associated genes. FURIN, MAN2A2, HDDC3, ALDH2, and TOMM40 were identified as feature genes for constructing the nomogram that provides …
We identified 73 genes that are linked to blood pressure and circulating lipids in the context of IS, and 16 are differentially expressed as …
MESH1 is a cytosolic NADPH phosphatase that regulates ferroptosis.
Ding CC, Rose J, Sun T, Wu J, Chen PH, Lin CC, Yang WH, Chen KY, Lee H, Xu E, Tian S, Akinwuntan J, Zhao J, Guan Z, Zhou P, Chi JT. Ding CC, et al. Nat Metab. 2020 Mar;2(3):270-277. doi: 10.1038/s42255-020-0181-1. Epub 2020 Mar 9. Nat Metab. 2020. PMID: 32462112 Free PMC article.
NADPH oxidase 4 is dispensable for skin myofibroblast differentiation and wound healing.
Siedlar AM, Seredenina T, Faivre A, Cambet Y, Stasia MJ, André-Lévigne D, Bochaton-Piallat ML, Pittet-Cuénod B, de Seigneux S, Krause KH, Modarressi A, Jaquet V. Siedlar AM, et al. Redox Biol. 2023 Apr;60:102609. doi: 10.1016/j.redox.2023.102609. Epub 2023 Jan 13. Redox Biol. 2023. PMID: 36708644 Free PMC article.
Transcriptomic analysis revealed upregulation of the mitochondrial protein Ucp2 and the stress-response protein Hddc3 in Nox4-deficient fibroblasts, which had however no impact on fibroblast bioenergetics. ...
Transcriptomic analysis revealed upregulation of the mitochondrial protein Ucp2 and the stress-response protein Hddc3 in Nox4-deficie …
Identification of novel candidate biomarkers and immune infiltration in polycystic ovary syndrome.
Na Z, Guo W, Song J, Feng D, Fang Y, Li D. Na Z, et al. J Ovarian Res. 2022 Jul 6;15(1):80. doi: 10.1186/s13048-022-01013-0. J Ovarian Res. 2022. PMID: 35794640 Free PMC article.
The two diagnostic biomarkers of PCOS identified by us were HD domain containing 3 (HDDC3) and syndecan 2 (SDC2; AUC, 0.918 and 0.816, respectively). ...Immune infiltration analysis indicated that decreased activated mast cells (P = 0.033) and increased eosinophils (P = 0. …
The two diagnostic biomarkers of PCOS identified by us were HD domain containing 3 (HDDC3) and syndecan 2 (SDC2; AUC, 0.918 and 0.816 …
ppGpp functions as an alarmone in metazoa.
Ito D, Kawamura H, Oikawa A, Ihara Y, Shibata T, Nakamura N, Asano T, Kawabata SI, Suzuki T, Masuda S. Ito D, et al. Commun Biol. 2020 Nov 13;3(1):671. doi: 10.1038/s42003-020-01368-4. Commun Biol. 2020. PMID: 33188280 Free PMC article.
A metazoan ortholog of SpoT hydrolyzes ppGpp and functions in starvation responses.
Sun D, Lee G, Lee JH, Kim HY, Rhee HW, Park SY, Kim KJ, Kim Y, Kim BY, Hong JI, Park C, Choy HE, Kim JH, Jeon YH, Chung J. Sun D, et al. Nat Struct Mol Biol. 2010 Oct;17(10):1188-94. doi: 10.1038/nsmb.1906. Epub 2010 Sep 5. Nat Struct Mol Biol. 2010. PMID: 20818390
Here we identify functional SpoT orthologs in metazoa (named Mesh1, encoded by HDDC3 in human and Q9VAM9 in Drosophila melanogaster) and reveal their structures and functions. ...
Here we identify functional SpoT orthologs in metazoa (named Mesh1, encoded by HDDC3 in human and Q9VAM9 in Drosophila melanogaster) …
Genome-wide association analysis to identify SNP markers affecting teat numbers in an F2 intercross population between Landrace and Korean native pigs.
Lee JB, Jung EJ, Park HB, Jin S, Seo DW, Ko MS, Cho IC, Lee JH, Lim HT. Lee JB, et al. Mol Biol Rep. 2014 Nov;41(11):7167-73. doi: 10.1007/s11033-014-3599-2. Epub 2014 Jul 24. Mol Biol Rep. 2014. PMID: 25055975
When a genome-wide threshold was determined using the Bonferroni method (P = 1.61 10(-6)), 38 single nucleotide polymorphism (SNP) markers in pig chromosome 7 (SSC7) were significantly associated with three teat number traits (total teat number, left teat number, and right teat n …
When a genome-wide threshold was determined using the Bonferroni method (P = 1.61 10(-6)), 38 single nucleotide polymorphism (SNP) markers i …
MicroRNA related polymorphisms and breast cancer risk.
Khan S, Greco D, Michailidou K, Milne RL, Muranen TA, Heikkinen T, Aaltonen K, Dennis J, Bolla MK, Liu J, Hall P, Irwanto A, Humphreys K, Li J, Czene K, Chang-Claude J, Hein R, Rudolph A, Seibold P, Flesch-Janys D, Fletcher O, Peto J, dos Santos Silva I, Johnson N, Gibson L, Aitken Z, Hopper JL, Tsimiklis H, Bui M, Makalic E, Schmidt DF, Southey MC, Apicella C, Stone J, Waisfisz Q, Meijers-Heijboer H, Adank MA, van der Luijt RB, Meindl A, Schmutzler RK, Müller-Myhsok B, Lichtner P, Turnbull C, Rahman N, Chanock SJ, Hunter DJ, Cox A, Cross SS, Reed MW, Schmidt MK, Broeks A, Van't Veer LJ, Hogervorst FB, Fasching PA, Schrauder MG, Ekici AB, Beckmann MW, Bojesen SE, Nordestgaard BG, Nielsen SF, Flyger H, Benitez J, Zamora PM, Perez JI, Haiman CA, Henderson BE, Schumacher F, Le Marchand L, Pharoah PD, Dunning AM, Shah M, Luben R, Brown J, Couch FJ, Wang X, Vachon C, Olson JE, Lambrechts D, Moisse M, Paridaens R, Christiaens MR, Guénel P, Truong T, Laurent-Puig P, Mulot C, Marme F, Burwinkel B, Schneeweiss A, Sohn C, Sawyer EJ, Tomlinson I, Kerin MJ, Miller N, Andrulis IL, Knight JA, Tchatchou S, Mulligan AM, Dörk T, Bogdanova NV, Antonenkova NN, Anton-Culver H, Darabi H, Eriksson M, G… See abstract for full author list ➔ Khan S, et al. PLoS One. 2014 Nov 12;9(11):e109973. doi: 10.1371/journal.pone.0109973. eCollection 2014. PLoS One. 2014. PMID: 25390939 Free PMC article.
Five miRNA binding site SNPs associated significantly with breast cancer risk: rs1045494 (odds ratio (OR) 0.92; 95% confidence interval (CI): 0.88-0.96), rs1052532 (OR 0.97; 95% CI: 0.95-0.99), rs10719 (OR 0.97; 95% CI: 0.94-0.99), rs4687554 (OR 0.97; 95% CI: 0.95-0.99, and rs313 …
Five miRNA binding site SNPs associated significantly with breast cancer risk: rs1045494 (odds ratio (OR) 0.92; 95% confidence interval (CI) …
11 results