Heasley LE - Search Results

1

Functional RNAi Screens Define Distinct Protein Kinase Vulnerabilities in EGFR-Dependent HNSCC Cell Lines.

Hinz TK, Kleczko EK, Singleton KR, Calhoun J, Marek LA, Kim J, Tan AC, Heasley LE. Hinz TK, et al. Among authors: heasley le. Mol Pharmacol. 2019 Dec;96(6):862-870. doi: 10.1124/mol.119.117804. Epub 2019 Sep 25. Mol Pharmacol. 2019. PMID: 31554698 Free PMC article.

2

Regulation of platinum-compound cytotoxicity by the c-Jun N-terminal kinase and c-Jun signaling pathway in small-cell lung cancer cells.

Levresse V, Marek L, Blumberg D, Heasley LE. Levresse V, et al. Among authors: heasley le. Mol Pharmacol. 2002 Sep;62(3):689-97. doi: 10.1124/mol.62.3.689. Mol Pharmacol. 2002. PMID: 12181446

3

Multiple signaling conduits regulate global differentiation-specific gene expression in PC12 cells.

Marek L, Levresse V, Amura C, Zentrich E, Van Putten V, Nemenoff RA, Heasley LE. Marek L, et al. Among authors: heasley le. J Cell Physiol. 2004 Dec;201(3):459-69. doi: 10.1002/jcp.20087. J Cell Physiol. 2004. PMID: 15389548

4

Restoration of Wnt-7a expression reverses non-small cell lung cancer cellular transformation through frizzled-9-mediated growth inhibition and promotion of cell differentiation.

Winn RA, Marek L, Han SY, Rodriguez K, Rodriguez N, Hammond M, Van Scoyk M, Acosta H, Mirus J, Barry N, Bren-Mattison Y, Van Raay TJ, Nemenoff RA, Heasley LE. Winn RA, et al. Among authors: heasley le. J Biol Chem. 2005 May 20;280(20):19625-34. doi: 10.1074/jbc.M409392200. Epub 2005 Feb 10. J Biol Chem. 2005. PMID: 15705594 Free article.

5

Inhibited neurogenesis in JNK1-deficient embryonic stem cells.

Amura CR, Marek L, Winn RA, Heasley LE. Amura CR, et al. Among authors: heasley le. Mol Cell Biol. 2005 Dec;25(24):10791-802. doi: 10.1128/MCB.25.24.10791-10802.2005. Mol Cell Biol. 2005. PMID: 16314504 Free PMC article.

6

Fibroblast growth factor (FGF) and FGF receptor-mediated autocrine signaling in non-small-cell lung cancer cells.

Marek L, Ware KE, Fritzsche A, Hercule P, Helton WR, Smith JE, McDermott LA, Coldren CD, Nemenoff RA, Merrick DT, Helfrich BA, Bunn PA Jr, Heasley LE. Marek L, et al. Among authors: heasley le. Mol Pharmacol. 2009 Jan;75(1):196-207. doi: 10.1124/mol.108.049544. Epub 2008 Oct 10. Mol Pharmacol. 2009. PMID: 18849352 Free PMC article.

7

Rapidly acquired resistance to EGFR tyrosine kinase inhibitors in NSCLC cell lines through de-repression of FGFR2 and FGFR3 expression.

Ware KE, Marshall ME, Heasley LR, Marek L, Hinz TK, Hercule P, Helfrich BA, Doebele RC, Heasley LE. Ware KE, et al. Among authors: heasley lr, heasley le. PLoS One. 2010 Nov 29;5(11):e14117. doi: 10.1371/journal.pone.0014117. PLoS One. 2010. PMID: 21152424 Free PMC article.

8

Protein kinase C δ is a downstream effector of oncogenic K-ras in lung tumors.

Symonds JM, Ohm AM, Carter CJ, Heasley LE, Boyle TA, Franklin WA, Reyland ME. Symonds JM, et al. Among authors: heasley le. Cancer Res. 2011 Mar 15;71(6):2087-97. doi: 10.1158/0008-5472.CAN-10-1511. Epub 2011 Feb 18. Cancer Res. 2011. PMID: 21335545 Free PMC article.

9

Fibroblast growth factor receptors are components of autocrine signaling networks in head and neck squamous cell carcinoma cells.

Marshall ME, Hinz TK, Kono SA, Singleton KR, Bichon B, Ware KE, Marek L, Frederick BA, Raben D, Heasley LE. Marshall ME, et al. Among authors: heasley le. Clin Cancer Res. 2011 Aug 1;17(15):5016-25. doi: 10.1158/1078-0432.CCR-11-0050. Epub 2011 Jun 14. Clin Cancer Res. 2011. PMID: 21673064 Free PMC article.

10

A receptor tyrosine kinase network composed of fibroblast growth factor receptors, epidermal growth factor receptor, v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, and hepatocyte growth factor receptor drives growth and survival of head and neck squamous carcinoma cell lines.

Singleton KR, Kim J, Hinz TK, Marek LA, Casás-Selves M, Hatheway C, Tan AC, DeGregori J, Heasley LE. Singleton KR, et al. Among authors: heasley le. Mol Pharmacol. 2013 Apr;83(4):882-93. doi: 10.1124/mol.112.084111. Epub 2013 Jan 31. Mol Pharmacol. 2013. PMID: 23371912 Free PMC article.

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