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Page 1
Quantifying the phenome-wide disease burden of obesity using electronic health records and genomics.
Robinson JR, Carroll RJ, Bastarache L, Chen Q, Pirruccello J, Mou Z, Wei WQ, Connolly J, Mentch F, Crane PK, Hebbring SJ, Crosslin DR, Gordon AS, Rosenthal EA, Stanaway IB, Hayes MG, Wei W, Petukhova L, Namjou-Khales B, Zhang G, Safarova MS, Walton NA, Still C, Bottinger EP, Loos RJF, Murphy SN, Jackson GP, Abumrad N, Kullo IJ, Jarvik GP, Larson EB, Weng C, Roden D, Khera AV, Denny JC. Robinson JR, et al. Among authors: hebbring sj. Obesity (Silver Spring). 2022 Dec;30(12):2477-2488. doi: 10.1002/oby.23561. Epub 2022 Nov 13. Obesity (Silver Spring). 2022. PMID: 36372681 Free PMC article.
Phenome-wide association studies (PheWASs) for functional variants.
Ye Z, Mayer J, Ivacic L, Zhou Z, He M, Schrodi SJ, Page D, Brilliant MH, Hebbring SJ. Ye Z, et al. Among authors: hebbring sj. Eur J Hum Genet. 2015 Apr;23(4):523-9. doi: 10.1038/ejhg.2014.123. Epub 2014 Jul 30. Eur J Hum Genet. 2015. PMID: 25074467 Free PMC article.
Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index.
Cronin RM, Field JR, Bradford Y, Shaffer CM, Carroll RJ, Mosley JD, Bastarache L, Edwards TL, Hebbring SJ, Lin S, Hindorff LA, Crane PK, Pendergrass SA, Ritchie MD, Crawford DC, Pathak J, Bielinski SJ, Carrell DS, Crosslin DR, Ledbetter DH, Carey DJ, Tromp G, Williams MS, Larson EB, Jarvik GP, Peissig PL, Brilliant MH, McCarty CA, Chute CG, Kullo IJ, Bottinger E, Chisholm R, Smith ME, Roden DM, Denny JC. Cronin RM, et al. Among authors: hebbring sj. Front Genet. 2014 Aug 5;5:250. doi: 10.3389/fgene.2014.00250. eCollection 2014. Front Genet. 2014. PMID: 25177340 Free PMC article.
Genome-Wide Association Study of Serum Creatinine Levels during Vancomycin Therapy.
Van Driest SL, McGregor TL, Velez Edwards DR, Saville BR, Kitchner TE, Hebbring SJ, Brilliant M, Jouni H, Kullo IJ, Creech CB, Kannankeril PJ, Vear SI, Brothers KB, Bowton EA, Shaffer CM, Patel N, Delaney JT, Bradford Y, Wilson S, Olson LM, Crawford DC, Potts AL, Ho RH, Roden DM, Denny JC. Van Driest SL, et al. Among authors: hebbring sj. PLoS One. 2015 Jun 1;10(6):e0127791. doi: 10.1371/journal.pone.0127791. eCollection 2015. PLoS One. 2015. PMID: 26030142 Free PMC article.
The phenotypic legacy of admixture between modern humans and Neandertals.
Simonti CN, Vernot B, Bastarache L, Bottinger E, Carrell DS, Chisholm RL, Crosslin DR, Hebbring SJ, Jarvik GP, Kullo IJ, Li R, Pathak J, Ritchie MD, Roden DM, Verma SS, Tromp G, Prato JD, Bush WS, Akey JM, Denny JC, Capra JA. Simonti CN, et al. Among authors: hebbring sj. Science. 2016 Feb 12;351(6274):737-41. doi: 10.1126/science.aad2149. Science. 2016. PMID: 26912863 Free PMC article.
Identifying genetically driven clinical phenotypes using linear mixed models.
Mosley JD, Witte JS, Larkin EK, Bastarache L, Shaffer CM, Karnes JH, Stein CM, Phillips E, Hebbring SJ, Brilliant MH, Mayer J, Ye Z, Roden DM, Denny JC. Mosley JD, et al. Among authors: hebbring sj. Nat Commun. 2016 Apr 25;7:11433. doi: 10.1038/ncomms11433. Nat Commun. 2016. PMID: 27109359 Free PMC article.
97 results