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Abrogation of donor T-cell IL-21 signaling leads to tissue-specific modulation of immunity and separation of GVHD from GVL.
Hanash AM, Kappel LW, Yim NL, Nejat RA, Goldberg GL, Smith OM, Rao UK, Dykstra L, Na IK, Holland AM, Dudakov JA, Liu C, Murphy GF, Leonard WJ, Heller G, van den Brink MR. Hanash AM, et al. Among authors: heller g. Blood. 2011 Jul 14;118(2):446-55. doi: 10.1182/blood-2010-07-294785. Epub 2011 May 19. Blood. 2011. PMID: 21596854 Free PMC article.
CCR2 is required for CD8-induced graft-versus-host disease.
Terwey TH, Kim TD, Kochman AA, Hubbard VM, Lu S, Zakrzewski JL, Ramirez-Montagut T, Eng JM, Muriglan SJ, Heller G, Murphy GF, Liu C, Budak-Alpdogan T, Alpdogan O, van den Brink MR. Terwey TH, et al. Among authors: heller g. Blood. 2005 Nov 1;106(9):3322-30. doi: 10.1182/blood-2005-05-1860. Epub 2005 Jul 21. Blood. 2005. PMID: 16037386 Free PMC article.
DNA immunization against tissue-restricted antigens enhances tumor immunity after allogeneic hemopoietic stem cell transplantation.
Perales MA, Diab A, Cohen AD, Huggins DW, Guevara-Patiño JA, Hubbard VM, Engelhorn ME, Kochman AA, Eng JM, Mortazavi F, Alpdogan O, Terwey TH, Heller G, Wolchok JD, Houghton AN, van den Brink MR. Perales MA, et al. Among authors: heller g. J Immunol. 2006 Sep 15;177(6):4159-67. doi: 10.4049/jimmunol.177.6.4159. J Immunol. 2006. PMID: 16951381
IFN-gamma and Fas ligand are required for graft-versus-tumor activity against renal cell carcinoma in the absence of lethal graft-versus-host disease.
Ramirez-Montagut T, Chow A, Kochman AA, Smith OM, Suh D, Sindhi H, Lu S, Borsotti C, Grubin J, Patel N, Terwey TH, Kim TD, Heller G, Murphy GF, Liu C, Alpdogan O, van den Brink MR. Ramirez-Montagut T, et al. Among authors: heller g. J Immunol. 2007 Aug 1;179(3):1669-80. doi: 10.4049/jimmunol.179.3.1669. J Immunol. 2007. PMID: 17641033
931 results