Hellinen L - Search Results

1

Inhibition of prolyl oligopeptidase: A promising pathway to prevent the progression of age-related macular degeneration.

Hellinen L, Koskela A, Vattulainen E, Liukkonen M, Wegler C, Treyer A, Handin N, Svensson R, Myöhänen T, Poso A, Kaarniranta K, Artursson P, Urtti A. Hellinen L, et al. Biomed Pharmacother. 2022 Feb;146:112501. doi: 10.1016/j.biopha.2021.112501. Epub 2021 Dec 7. Biomed Pharmacother. 2022. PMID: 34891119 Free article.

2

The effect of prolyl oligopeptidase inhibitors on alpha-synuclein aggregation and autophagy cannot be predicted by their inhibitory efficacy.

Kilpeläinen TP, Hellinen L, Vrijdag J, Yan X, Svarcbahs R, Vellonen KS, Lambeir AM, Huttunen H, Urtti A, Wallen EAA, Myöhänen TT. Kilpeläinen TP, et al. Among authors: hellinen l. Biomed Pharmacother. 2020 Aug;128:110253. doi: 10.1016/j.biopha.2020.110253. Epub 2020 May 22. Biomed Pharmacother. 2020. PMID: 32447211 Free article.

3

Characterization of artificially re-pigmented ARPE-19 retinal pigment epithelial cell model.

Hellinen L, Hagström M, Knuutila H, Ruponen M, Urtti A, Reinisalo M. Hellinen L, et al. Sci Rep. 2019 Sep 24;9(1):13761. doi: 10.1038/s41598-019-50324-8. Sci Rep. 2019. PMID: 31551473 Free PMC article.

4

Mechanisms of cellular retention of melanin bound drugs: Experiments and computational modeling.

Bahrpeyma S, Reinisalo M, Hellinen L, Auriola S, Del Amo EM, Urtti A. Bahrpeyma S, et al. Among authors: hellinen l. J Control Release. 2022 Aug;348:760-770. doi: 10.1016/j.jconrel.2022.05.059. Epub 2022 Jun 25. J Control Release. 2022. PMID: 35738465 Free article.

5

Retinal Pigment Epithelial Cell Line with Fast Differentiation and Improved Barrier Properties.

Hellinen L, Pirskanen L, Tengvall-Unadike U, Urtti A, Reinisalo M. Hellinen L, et al. Pharmaceutics. 2019 Aug 13;11(8):412. doi: 10.3390/pharmaceutics11080412. Pharmaceutics. 2019. PMID: 31412689 Free PMC article. Retracted.

6

Quantitative Protein Expression in the Human Retinal Pigment Epithelium: Comparison Between Apical and Basolateral Plasma Membranes With Emphasis on Transporters.

Hellinen L, Sato K, Reinisalo M, Kidron H, Rilla K, Tachikawa M, Uchida Y, Terasaki T, Urtti A. Hellinen L, et al. Invest Ophthalmol Vis Sci. 2019 Dec 2;60(15):5022-5034. doi: 10.1167/iovs.19-27328. Invest Ophthalmol Vis Sci. 2019. PMID: 31791063

7

Prodrug Approach for Posterior Eye Drug Delivery: Synthesis of Novel Ganciclovir Prodrugs and in Vitro Screening with Cassette Dosing.

Heikkinen EM, Ruponen M, Jasper LM, Leppänen J, Hellinen L, Urtti A, Auriola S, Rautio J, Vellonen KS. Heikkinen EM, et al. Among authors: hellinen l. Mol Pharm. 2020 Jun 1;17(6):1945-1953. doi: 10.1021/acs.molpharmaceut.0c00037. Epub 2020 May 5. Mol Pharm. 2020. PMID: 32320251

8

Microscale Thermophoresis as a Screening Tool to Predict Melanin Binding of Drugs.

Hellinen L, Bahrpeyma S, Rimpelä AK, Hagström M, Reinisalo M, Urtti A. Hellinen L, et al. Pharmaceutics. 2020 Jun 16;12(6):554. doi: 10.3390/pharmaceutics12060554. Pharmaceutics. 2020. PMID: 32560065 Free PMC article.

9

Retraction: Hellinen et al. Retinal Pigment Epithelial Cell Line with Fast Differentiation and Improved Barrier Properties. Pharmaceutics 2019, 11, 412.

Hellinen L, Pirskanen L, Tengvall-Unadike U, Urtti A, Reinisalo M. Hellinen L, et al. Pharmaceutics. 2022 Mar 14;14(3):635. doi: 10.3390/pharmaceutics14030635. Pharmaceutics. 2022. PMID: 35297821 Free PMC article.

10

Expression, activity and pharmacokinetic impact of ocular transporters.

Vellonen KS, Hellinen L, Mannermaa E, Ruponen M, Urtti A, Kidron H. Vellonen KS, et al. Among authors: hellinen l. Adv Drug Deliv Rev. 2018 Feb 15;126:3-22. doi: 10.1016/j.addr.2017.12.009. Epub 2017 Dec 14. Adv Drug Deliv Rev. 2018. PMID: 29248478 Review.

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