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Structural studies of the effect that dimethyl sulfoxide (DMSO) has on cisplatin and carboplatin binding to histidine in a protein.
Tanley SW, Schreurs AM, Kroon-Batenburg LM, Meredith J, Prendergast R, Walsh D, Bryant P, Levy C, Helliwell JR. Tanley SW, et al. Among authors: helliwell jr. Acta Crystallogr D Biol Crystallogr. 2012 May;68(Pt 5):601-12. doi: 10.1107/S0907444912006907. Epub 2012 Apr 17. Acta Crystallogr D Biol Crystallogr. 2012. PMID: 22525758
The binding of platinum hexahalides (Cl, Br and I) to hen egg-white lysozyme and the chemical transformation of the PtI6 octahedral complex to a PtI3 moiety bound to His15.
Tanley SW, Starkey LV, Lamplough L, Kaenket S, Helliwell JR. Tanley SW, et al. Among authors: helliwell jr. Acta Crystallogr F Struct Biol Commun. 2014 Sep;70(Pt 9):1132-4. doi: 10.1107/S2053230X14014009. Epub 2014 Aug 29. Acta Crystallogr F Struct Biol Commun. 2014. PMID: 25195880 Free PMC article.
Carboplatin binding to histidine.
Tanley SW, Diederichs K, Kroon-Batenburg LM, Levy C, Schreurs AM, Helliwell JR. Tanley SW, et al. Among authors: helliwell jr. Acta Crystallogr F Struct Biol Commun. 2014 Sep;70(Pt 9):1135-42. doi: 10.1107/S2053230X14016161. Epub 2014 Aug 29. Acta Crystallogr F Struct Biol Commun. 2014. PMID: 25195881 Free PMC article.
Response from Tanley et al. to Crystallography and chemistry should always go together: a cautionary tale of protein complexes with cisplatin and carboplatin.
Tanley SW, Diederichs K, Kroon-Batenburg LM, Levy C, Schreurs AM, Helliwell JR. Tanley SW, et al. Among authors: helliwell jr. Acta Crystallogr D Biol Crystallogr. 2015 Sep;71(Pt 9):1982-3. doi: 10.1107/S1399004715014340. Epub 2015 Aug 28. Acta Crystallogr D Biol Crystallogr. 2015. PMID: 26327388 No abstract available.
165 results