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Vulnerabilities of mutant SWI/SNF complexes in cancer.
Cancer Cell. 2014 Sep 8;26(3):309-317. doi: 10.1016/j.ccr.2014.07.018.
Cancer Cell. 2014.
PMID: 25203320
Free PMC article.
Review.
Swi/Snf chromatin remodeling/tumor suppressor complex establishes nucleosome occupancy at target promoters.
Tolstorukov MY, Sansam CG, Lu P, Koellhoffer EC, Helming KC, Alver BH, Tillman EJ, Evans JA, Wilson BG, Park PJ, Roberts CW.
Tolstorukov MY, et al. Among authors: helming kc.
Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10165-70. doi: 10.1073/pnas.1302209110. Epub 2013 May 30.
Proc Natl Acad Sci U S A. 2013.
PMID: 23723349
Free PMC article.
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ARID1B is a specific vulnerability in ARID1A-mutant cancers.
Helming KC, Wang X, Wilson BG, Vazquez F, Haswell JR, Manchester HE, Kim Y, Kryukov GV, Ghandi M, Aguirre AJ, Jagani Z, Wang Z, Garraway LA, Hahn WC, Roberts CW.
Helming KC, et al.
Nat Med. 2014 Mar;20(3):251-4. doi: 10.1038/nm.3480. Epub 2014 Feb 23.
Nat Med. 2014.
PMID: 24562383
Free PMC article.
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Residual complexes containing SMARCA2 (BRM) underlie the oncogenic drive of SMARCA4 (BRG1) mutation.
Wilson BG, Helming KC, Wang X, Kim Y, Vazquez F, Jagani Z, Hahn WC, Roberts CW.
Wilson BG, et al. Among authors: helming kc.
Mol Cell Biol. 2014 Mar;34(6):1136-44. doi: 10.1128/MCB.01372-13. Epub 2014 Jan 13.
Mol Cell Biol. 2014.
PMID: 24421395
Free PMC article.
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Deletion of AIF1 but not of YCA1/MCA1 protects Saccharomyces cerevisiae and Candida albicans cells from caspofungin-induced programmed cell death.
Chin C, Donaghey F, Helming K, McCarthy M, Rogers S, Austriaco N.
Chin C, et al.
Microb Cell. 2014 Jan 15;1(2):58-63. doi: 10.15698/mic2014.01.119.
Microb Cell. 2014.
PMID: 28357223
Free PMC article.
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