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Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer's disease.
Venegas C, Kumar S, Franklin BS, Dierkes T, Brinkschulte R, Tejera D, Vieira-Saecker A, Schwartz S, Santarelli F, Kummer MP, Griep A, Gelpi E, Beilharz M, Riedel D, Golenbock DT, Geyer M, Walter J, Latz E, Heneka MT. Venegas C, et al. Among authors: heneka mt. Nature. 2017 Dec 20;552(7685):355-361. doi: 10.1038/nature25158. Nature. 2017. PMID: 29293211
Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma.
Sastre M, Dewachter I, Rossner S, Bogdanovic N, Rosen E, Borghgraef P, Evert BO, Dumitrescu-Ozimek L, Thal DR, Landreth G, Walter J, Klockgether T, van Leuven F, Heneka MT. Sastre M, et al. Among authors: heneka mt. Proc Natl Acad Sci U S A. 2006 Jan 10;103(2):443-8. doi: 10.1073/pnas.0503839103. Epub 2006 Jan 3. Proc Natl Acad Sci U S A. 2006. PMID: 16407166 Free PMC article.
PPARs in Alzheimer's Disease.
Kummer MP, Heneka MT. Kummer MP, et al. Among authors: heneka mt. PPAR Res. 2008;2008:403896. doi: 10.1155/2008/403896. PPAR Res. 2008. PMID: 18645613 Free PMC article.
Sepsis causes neuroinflammation and concomitant decrease of cerebral metabolism.
Semmler A, Hermann S, Mormann F, Weberpals M, Paxian SA, Okulla T, Schäfers M, Kummer MP, Klockgether T, Heneka MT. Semmler A, et al. Among authors: heneka mt. J Neuroinflammation. 2008 Sep 15;5:38. doi: 10.1186/1742-2094-5-38. J Neuroinflammation. 2008. PMID: 18793399 Free PMC article.
Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis.
Tamboli IY, Prager K, Thal DR, Thelen KM, Dewachter I, Pietrzik CU, St George-Hyslop P, Sisodia SS, De Strooper B, Heneka MT, Filippov MA, Müller U, van Leuven F, Lütjohann D, Walter J. Tamboli IY, et al. Among authors: heneka mt. J Neurosci. 2008 Nov 12;28(46):12097-106. doi: 10.1523/JNEUROSCI.2635-08.2008. J Neurosci. 2008. PMID: 19005074 Free PMC article.
306 results