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HSP72 protects against obesity-induced insulin resistance.
Chung J, Nguyen AK, Henstridge DC, Holmes AG, Chan MH, Mesa JL, Lancaster GI, Southgate RJ, Bruce CR, Duffy SJ, Horvath I, Mestril R, Watt MJ, Hooper PL, Kingwell BA, Vigh L, Hevener A, Febbraio MA. Chung J, et al. Among authors: henstridge dc. Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1739-44. doi: 10.1073/pnas.0705799105. Epub 2008 Jan 25. Proc Natl Acad Sci U S A. 2008. PMID: 18223156 Free PMC article.
Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance.
Matthews VB, Allen TL, Risis S, Chan MH, Henstridge DC, Watson N, Zaffino LA, Babb JR, Boon J, Meikle PJ, Jowett JB, Watt MJ, Jansson JO, Bruce CR, Febbraio MA. Matthews VB, et al. Among authors: henstridge dc. Diabetologia. 2010 Nov;53(11):2431-41. doi: 10.1007/s00125-010-1865-y. Epub 2010 Aug 11. Diabetologia. 2010. PMID: 20697689
Myeloid-specific estrogen receptor alpha deficiency impairs metabolic homeostasis and accelerates atherosclerotic lesion development.
Ribas V, Drew BG, Le JA, Soleymani T, Daraei P, Sitz D, Mohammad L, Henstridge DC, Febbraio MA, Hewitt SC, Korach KS, Bensinger SJ, Hevener AL. Ribas V, et al. Among authors: henstridge dc. Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16457-62. doi: 10.1073/pnas.1104533108. Epub 2011 Sep 7. Proc Natl Acad Sci U S A. 2011. PMID: 21900603 Free PMC article.
Activating HSP72 in rodent skeletal muscle increases mitochondrial number and oxidative capacity and decreases insulin resistance.
Henstridge DC, Bruce CR, Drew BG, Tory K, Kolonics A, Estevez E, Chung J, Watson N, Gardner T, Lee-Young RS, Connor T, Watt MJ, Carpenter K, Hargreaves M, McGee SL, Hevener AL, Febbraio MA. Henstridge DC, et al. Diabetes. 2014 Jun;63(6):1881-94. doi: 10.2337/db13-0967. Epub 2014 Jan 15. Diabetes. 2014. PMID: 24430435 Free PMC article.
The E3 ligase MARCH5 is a PPARγ target gene that regulates mitochondria and metabolism in adipocytes.
Bond ST, Moody SC, Liu Y, Civelek M, Villanueva CJ, Gregorevic P, Kingwell BA, Hevener AL, Lusis AJ, Henstridge DC, Calkin AC, Drew BG. Bond ST, et al. Among authors: henstridge dc. Am J Physiol Endocrinol Metab. 2019 Feb 1;316(2):E293-E304. doi: 10.1152/ajpendo.00394.2018. Epub 2018 Dec 4. Am J Physiol Endocrinol Metab. 2019. PMID: 30512991 Free PMC article.
Yap regulates skeletal muscle fatty acid oxidation and adiposity in metabolic disease.
Watt KI, Henstridge DC, Ziemann M, Sim CB, Montgomery MK, Samocha-Bonet D, Parker BL, Dodd GT, Bond ST, Salmi TM, Lee RS, Thomson RE, Hagg A, Davey JR, Qian H, Koopman R, El-Osta A, Greenfield JR, Watt MJ, Febbraio MA, Drew BG, Cox AG, Porrello ER, Harvey KF, Gregorevic P. Watt KI, et al. Among authors: henstridge dc. Nat Commun. 2021 May 17;12(1):2887. doi: 10.1038/s41467-021-23240-7. Nat Commun. 2021. PMID: 34001905 Free PMC article.
84 results