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Hypothalamic leptin action is mediated by histone deacetylase 5.
Kabra DG, Pfuhlmann K, García-Cáceres C, Schriever SC, Casquero García V, Kebede AF, Fuente-Martin E, Trivedi C, Heppner K, Uhlenhaut NH, Legutko B, Kabra UD, Gao Y, Yi CX, Quarta C, Clemmensen C, Finan B, Müller TD, Meyer CW, Paez-Pereda M, Stemmer K, Woods SC, Perez-Tilve D, Schneider R, Olson EN, Tschöp MH, Pfluger PT. Kabra DG, et al. Among authors: heppner k. Nat Commun. 2016 Feb 29;7:10782. doi: 10.1038/ncomms10782. Nat Commun. 2016. PMID: 26923837 Free PMC article.
The orphan receptor Gpr83 regulates systemic energy metabolism via ghrelin-dependent and ghrelin-independent mechanisms.
Müller TD, Müller A, Yi CX, Habegger KM, Meyer CW, Gaylinn BD, Finan B, Heppner K, Trivedi C, Bielohuby M, Abplanalp W, Meyer F, Piechowski CL, Pratzka J, Stemmer K, Holland J, Hembree J, Bhardwaj N, Raver C, Ottaway N, Krishna R, Sah R, Sallee FR, Woods SC, Perez-Tilve D, Bidlingmaier M, Thorner MO, Krude H, Smiley D, DiMarchi R, Hofmann S, Pfluger PT, Kleinau G, Biebermann H, Tschöp MH. Müller TD, et al. Among authors: heppner k. Nat Commun. 2013;4:1968. doi: 10.1038/ncomms2968. Nat Commun. 2013. PMID: 23744028 Free PMC article.
The role of ghrelin in the control of energy balance.
Kirchner H, Heppner KM, Tschöp MH. Kirchner H, et al. Handb Exp Pharmacol. 2012;(209):161-84. doi: 10.1007/978-3-642-24716-3_7. Handb Exp Pharmacol. 2012. PMID: 22249814 Review.
Fibroblast growth factor 21 mediates specific glucagon actions.
Habegger KM, Stemmer K, Cheng C, Müller TD, Heppner KM, Ottaway N, Holland J, Hembree JL, Smiley D, Gelfanov V, Krishna R, Arafat AM, Konkar A, Belli S, Kapps M, Woods SC, Hofmann SM, D'Alessio D, Pfluger PT, Perez-Tilve D, Seeley RJ, Konishi M, Itoh N, Kharitonenkov A, Spranger J, DiMarchi RD, Tschöp MH. Habegger KM, et al. Among authors: heppner km. Diabetes. 2013 May;62(5):1453-63. doi: 10.2337/db12-1116. Epub 2013 Jan 10. Diabetes. 2013. PMID: 23305646 Free PMC article. Clinical Trial.
Ghrelin-induced adiposity is independent of orexigenic effects.
Perez-Tilve D, Heppner K, Kirchner H, Lockie SH, Woods SC, Smiley DL, Tschöp M, Pfluger P. Perez-Tilve D, et al. Among authors: heppner k. FASEB J. 2011 Aug;25(8):2814-22. doi: 10.1096/fj.11-183632. Epub 2011 May 4. FASEB J. 2011. PMID: 21543764 Free PMC article.
Tachykinin-1 in the central nervous system regulates adiposity in rodents.
Trivedi C, Shan X, Tung YC, Kabra D, Holland J, Amburgy S, Heppner K, Kirchner H, Yeo GS, Perez-Tilve D. Trivedi C, et al. Among authors: heppner k. Endocrinology. 2015 May;156(5):1714-23. doi: 10.1210/en.2014-1781. Epub 2015 Mar 9. Endocrinology. 2015. PMID: 25751638 Free PMC article.
Glucagon regulation of energy metabolism.
Heppner KM, Habegger KM, Day J, Pfluger PT, Perez-Tilve D, Ward B, Gelfanov V, Woods SC, DiMarchi R, Tschöp M. Heppner KM, et al. Physiol Behav. 2010 Jul 14;100(5):545-8. doi: 10.1016/j.physbeh.2010.03.019. Epub 2010 Apr 8. Physiol Behav. 2010. PMID: 20381509 Review.
41 results