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Page 1
Modeling human mitochondrial diseases in flies.
Sánchez-Martínez A, Luo N, Clemente P, Adán C, Hernández-Sierra R, Ochoa P, Fernández-Moreno MA, Kaguni LS, Garesse R. Sánchez-Martínez A, et al. Among authors: hernandez sierra r. Biochim Biophys Acta. 2006 Sep-Oct;1757(9-10):1190-8. doi: 10.1016/j.bbabio.2006.05.008. Epub 2006 May 13. Biochim Biophys Acta. 2006. PMID: 16806050 Free PMC article. Review.
Over-expression of the catalytic core of mitochondrial DNA (mtDNA) polymerase in the nervous system of Drosophila melanogaster reduces median life span by inducing mtDNA depletion.
Martínez-Azorín F, Calleja M, Hernández-Sierra R, Farr CL, Kaguni LS, Garesse R. Martínez-Azorín F, et al. Among authors: hernandez sierra r. J Neurochem. 2008 Apr;105(1):165-76. doi: 10.1111/j.1471-4159.2007.05122.x. Epub 2007 Nov 12. J Neurochem. 2008. PMID: 17999718 Free PMC article.
Coiled coil domain-containing protein 56 (CCDC56) is a novel mitochondrial protein essential for cytochrome c oxidase function.
Peralta S, Clemente P, Sánchez-Martínez A, Calleja M, Hernández-Sierra R, Matsushima Y, Adán C, Ugalde C, Fernández-Moreno MÁ, Kaguni LS, Garesse R. Peralta S, et al. Among authors: hernandez sierra r. J Biol Chem. 2012 Jul 13;287(29):24174-85. doi: 10.1074/jbc.M112.343764. Epub 2012 May 18. J Biol Chem. 2012. PMID: 22610097 Free PMC article.
Functional Characterization of Three Concomitant MtDNA LHON Mutations Shows No Synergistic Effect on Mitochondrial Activity.
Cruz-Bermúdez A, Vicente-Blanco RJ, Hernández-Sierra R, Montero M, Alvarez J, González Manrique M, Blázquez A, Martín MA, Ayuso C, Garesse R, Fernández-Moreno MA. Cruz-Bermúdez A, et al. Among authors: hernandez sierra r. PLoS One. 2016 Jan 19;11(1):e0146816. doi: 10.1371/journal.pone.0146816. eCollection 2016. PLoS One. 2016. PMID: 26784702 Free PMC article.
Hypoxia compensates cell cycle arrest with progenitor differentiation during angiogenesis.
Acosta-Iborra B, Tiana M, Maeso-Alonso L, Hernández-Sierra R, Herranz G, Santamaria A, Rey C, Luna R, Puente-Santamaria L, Marques MM, Marin MC, Del Peso L, Jiménez B. Acosta-Iborra B, et al. Among authors: hernandez sierra r. FASEB J. 2020 May;34(5):6654-6674. doi: 10.1096/fj.201903082R. Epub 2020 Mar 29. FASEB J. 2020. PMID: 32223018 Free article.