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The Alleviating Effect of Herniarin Against Ionizing Radiation-Induced Genotoxicity and Cytotoxicity in Human Peripheral Blood Lymphocytes.
Al Fares E, Sanikidze T, Kalmakhelidze S, Topuria D, Mansi L, Kitson S, Molazadeh M. Al Fares E, et al. Curr Radiopharm. 2022;15(2):141-147. doi: 10.2174/1874471014666211012104808. Curr Radiopharm. 2022. PMID: 34636317
BACKGROUND AND OBJECTIVE: Herniarin is a simple coumarin that is found naturally in some plant species. ...METHODS: Herniarin was added to human lymphocytes before irradiation with a dose of 2 Gy of Xrays. ...
BACKGROUND AND OBJECTIVE: Herniarin is a simple coumarin that is found naturally in some plant species. ...METHODS: Herniarin
Neuroprotective effect of herniarin following transient focal cerebral ischemia in rats.
Asgharzade S, Khorrami MB, Forouzanfar F. Asgharzade S, et al. Metab Brain Dis. 2021 Dec;36(8):2505-2510. doi: 10.1007/s11011-021-00841-1. Epub 2021 Sep 14. Metab Brain Dis. 2021. PMID: 34519909
Herniarin at doses of 10 and 20 mg/kg was administered through intraperitoneal injection for 7 days before MCAO induction. ...Moreover, herniarin pretreatment decreased the levels of IL-1beta and TNF-alpha in the brain tissues of MCAO rats. ...
Herniarin at doses of 10 and 20 mg/kg was administered through intraperitoneal injection for 7 days before MCAO induction. ...Moreove
Enhancement of cisplatin cytotoxicity in combination with herniarin in vitro.
Haghighitalab A, Matin MM, Bahrami AR, Iranshahi M, Haghighi F, Porsa H. Haghighitalab A, et al. Drug Chem Toxicol. 2014 Apr;37(2):156-62. doi: 10.3109/01480545.2013.834354. Epub 2013 Oct 14. Drug Chem Toxicol. 2014. PMID: 24116377
In this study, the enhancing effects of herniarin on cisplatin cytotoxicity were investigated. Cytotoxicity of herniarin on transitional cell carcinoma (TCC) cells was first investigated in comparison with umbelliferone, the parent compound for a large number of cou …
In this study, the enhancing effects of herniarin on cisplatin cytotoxicity were investigated. Cytotoxicity of herniarin on tr …
The protective effect of herniarin on genotoxicity and apoptosis induced by cisplatin in bone marrow cells of rats.
Salehcheh M, Safari O, Khodayar MJ, Mojiri-Forushani H, Cheki M. Salehcheh M, et al. Drug Chem Toxicol. 2022 Jul;45(4):1470-1475. doi: 10.1080/01480545.2020.1842883. Epub 2020 Nov 3. Drug Chem Toxicol. 2022. PMID: 33143479
Herniarin is a member of simple coumarins, which are a group of common secondary metabolites in plants. ...Furthermore, herniarin significantly increased the levels of both red and white blood cells in peripheral blood. ...
Herniarin is a member of simple coumarins, which are a group of common secondary metabolites in plants. ...Furthermore, herniarin
Herniarin-loaded solid lipid nanoparticles: promising molecular mechanism and therapeutic potential against pancreatic cancer line.
Delkhah AMD, Karimi E, Farivar S. Delkhah AMD, et al. Mol Biol Rep. 2023 Aug;50(8):6469-6479. doi: 10.1007/s11033-023-08560-9. Epub 2023 Jun 16. Mol Biol Rep. 2023. PMID: 37326747
BACKGROUND: The notion of cancer therapy is intrinsically subjected to multiple challenges due to the drug resistance and drug toxicity for normal tissues. Herniarin (7-methoxycoumarin) belongs to the naturally occurring aromatic phytochemicals and coumarins. ...According …
BACKGROUND: The notion of cancer therapy is intrinsically subjected to multiple challenges due to the drug resistance and drug toxicity for …
The antioxidant, anti-angiogenic, and anticancer impact of chitosan-coated herniarin-graphene oxide nanoparticles (CHG-NPs).
Jasim LMM, Homayouni Tabrizi M, Darabi E, Jaseem MMM. Jasim LMM, et al. Heliyon. 2023 Sep 9;9(9):e20042. doi: 10.1016/j.heliyon.2023.e20042. eCollection 2023 Sep. Heliyon. 2023. PMID: 37809932 Free PMC article.
BACKGROUND: Herniarin, a simple coumarin found in chamomile leaf rosettes is known as the oxidative stress protector. ...METHOD: The Chitosan-coated Herniarin-Graphene oxide nanoparticles (CHG-NPs) were designed, produced, and characterized utilizing DLS, FESEM, FTI …
BACKGROUND: Herniarin, a simple coumarin found in chamomile leaf rosettes is known as the oxidative stress protector. ...METHOD: The …
Biosynthesis of coumarin and herniarin in lavender.
BROWN SA. BROWN SA. Science. 1962 Sep 21;137(3534):977-8. doi: 10.1126/science.137.3534.977. Science. 1962. PMID: 13873722
Coumarin and herniarin are formed in lavender from labeled o- and p-coumaric acids, respectively. At least part of the herniarin exists in lavender as a glycoside, presumably a 4-methoxycoumarinic acid glycoside, which yields free herniarin on hydrolysis. ...
Coumarin and herniarin are formed in lavender from labeled o- and p-coumaric acids, respectively. At least part of the herniarin
Anti-Inflammatory and Neuroprotective Effects of Standardized Fractions in Herniarin and Daphnoretin from Distictis buccinatoria.
Liliana Porras-Dávila S, Zamilpa A, Jiménez-Ferrer E, Jiménez-Aparicio A, Alejandra Santillan-Urquiza M, Díaz-Patricio F, Herrera-Ruiz M. Liliana Porras-Dávila S, et al. Chem Biodivers. 2023 May;20(5):e202200969. doi: 10.1002/cbdv.202200969. Chem Biodivers. 2023. PMID: 36973180
The inhibition of local edema was: F1 (73.6 %), F2 (57 %), F3 (62.61 %), F4 (87.3 %), and F5 (93.57 %). Terpene fraction inhibited at 89.60 %, herniarin at 86.92 % (Emax 99.01 %, ED50 0.35 mg ear(-1) ), and daphnoretin at 86.41 %. ...D. buccinatoria has neuroprotective act …
The inhibition of local edema was: F1 (73.6 %), F2 (57 %), F3 (62.61 %), F4 (87.3 %), and F5 (93.57 %). Terpene fraction inhibited at 89.60 …
Comparison of various techniques for the extraction of umbelliferone and herniarin in Matricaria chamomilla processing fractions.
Molnar M, Mendešević N, Šubarić D, Banjari I, Jokić S. Molnar M, et al. Chem Cent J. 2017 Aug 5;11(1):78. doi: 10.1186/s13065-017-0308-y. Chem Cent J. 2017. PMID: 29086851 Free PMC article.
Therefore, chamomile extracts with certain herniarin and umbelliferone content could be of interest for application in pharmaceutical and cosmetic products. ...Umbelliferone and herniarin content was determined by high performance liquid chromatography (HPLC). ...
Therefore, chamomile extracts with certain herniarin and umbelliferone content could be of interest for application in pharmaceutical …
Synthesis of umbelliferone derivatives in Escherichia coli and their biological activities.
Chu LL, Pandey RP, Lim HN, Jung HJ, Thuan NH, Kim TS, Sohng JK. Chu LL, et al. J Biol Eng. 2017 Apr 5;11:15. doi: 10.1186/s13036-017-0056-5. eCollection 2017. J Biol Eng. 2017. PMID: 28396694 Free PMC article.
RESULTS: Three umbelliferone derivatives (esculetin, skimmin, and herniarin) were generated through enzymatic and whole cell catalysis. ...The water solubility of esculetin and skimmin were 1.28-folds and 3.98-folds as high as umbelliferone, respectively, whereas hernia
RESULTS: Three umbelliferone derivatives (esculetin, skimmin, and herniarin) were generated through enzymatic and whole cell catalysi …
86 results