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Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3⁺ regulatory T cells.
Pierson W, Cauwe B, Policheni A, Schlenner SM, Franckaert D, Berges J, Humblet-Baron S, Schönefeldt S, Herold MJ, Hildeman D, Strasser A, Bouillet P, Lu LF, Matthys P, Freitas AA, Luther RJ, Weaver CT, Dooley J, Gray DH, Liston A. Pierson W, et al. Among authors: herold mj. Nat Immunol. 2013 Sep;14(9):959-65. doi: 10.1038/ni.2649. Epub 2013 Jul 14. Nat Immunol. 2013. PMID: 23852275 Free PMC article.
Targeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in p53.
Kelly GL, Grabow S, Glaser SP, Fitzsimmons L, Aubrey BJ, Okamoto T, Valente LJ, Robati M, Tai L, Fairlie WD, Lee EF, Lindstrom MS, Wiman KG, Huang DC, Bouillet P, Rowe M, Rickinson AB, Herold MJ, Strasser A. Kelly GL, et al. Among authors: herold mj. Genes Dev. 2014 Jan 1;28(1):58-70. doi: 10.1101/gad.232009.113. Genes Dev. 2014. PMID: 24395247 Free PMC article.
It's not over until the FAT lady sings.
Herold MJ, Strasser A. Herold MJ, et al. EMBO J. 2014 Feb 3;33(3):173-5. doi: 10.1002/embj.201387542. Epub 2014 Jan 17. EMBO J. 2014. PMID: 24442638 Free PMC article.
151 results