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Purification and proteomics of pathogen-modified vacuoles and membranes.
Herweg JA, Hansmeier N, Otto A, Geffken AC, Subbarayal P, Prusty BK, Becher D, Hensel M, Schaible UE, Rudel T, Hilbi H. Herweg JA, et al. Front Cell Infect Microbiol. 2015 Jun 2;5:48. doi: 10.3389/fcimb.2015.00048. eCollection 2015. Front Cell Infect Microbiol. 2015. PMID: 26082896 Free PMC article. Review.
Interaction of Chlamydiae with human macrophages.
Herweg JA, Rudel T. Herweg JA, et al. FEBS J. 2016 Feb;283(4):608-18. doi: 10.1111/febs.13609. Epub 2015 Dec 24. FEBS J. 2016. PMID: 26613554 Free article. Review.
Inhibitors of retrograde trafficking active against ricin and Shiga toxins also protect cells from several viruses, Leishmania and Chlamydiales.
Gupta N, Noël R, Goudet A, Hinsinger K, Michau A, Pons V, Abdelkafi H, Secher T, Shima A, Shtanko O, Sakurai Y, Cojean S, Pomel S, Liévin-Le Moal V, Leignel V, Herweg JA, Fischer A, Johannes L, Harrison K, Beard PM, Clayette P, Le Grand R, Rayner JO, Rudel T, Vacus J, Loiseau PM, Davey RA, Oswald E, Cintrat JC, Barbier J, Gillet D. Gupta N, et al. Among authors: herweg ja. Chem Biol Interact. 2017 Apr 1;267:96-103. doi: 10.1016/j.cbi.2016.10.005. Epub 2016 Oct 3. Chem Biol Interact. 2017. PMID: 27712998
ABMA, a small molecule that inhibits intracellular toxins and pathogens by interfering with late endosomal compartments.
Wu Y, Pons V, Goudet A, Panigai L, Fischer A, Herweg JA, Kali S, Davey RA, Laporte J, Bouclier C, Yousfi R, Aubenque C, Merer G, Gobbo E, Lopez R, Gillet C, Cojean S, Popoff MR, Clayette P, Le Grand R, Boulogne C, Tordo N, Lemichez E, Loiseau PM, Rudel T, Sauvaire D, Cintrat JC, Gillet D, Barbier J. Wu Y, et al. Among authors: herweg ja. Sci Rep. 2017 Nov 14;7(1):15567. doi: 10.1038/s41598-017-15466-7. Sci Rep. 2017. PMID: 29138439 Free PMC article.