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Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic Obesity.
Dalgaard K, Landgraf K, Heyne S, Lempradl A, Longinotto J, Gossens K, Ruf M, Orthofer M, Strogantsev R, Selvaraj M, Lu TT, Casas E, Teperino R, Surani MA, Zvetkova I, Rimmington D, Tung YC, Lam B, Larder R, Yeo GS, O'Rahilly S, Vavouri T, Whitelaw E, Penninger JM, Jenuwein T, Cheung CL, Ferguson-Smith AC, Coll AP, Körner A, Pospisilik JA. Dalgaard K, et al. Among authors: heyne s. Cell. 2016 Jan 28;164(3):353-64. doi: 10.1016/j.cell.2015.12.025. Cell. 2016. PMID: 26824653 Free PMC article.
Paternal diet defines offspring chromatin state and intergenerational obesity.
Öst A, Lempradl A, Casas E, Weigert M, Tiko T, Deniz M, Pantano L, Boenisch U, Itskov PM, Stoeckius M, Ruf M, Rajewsky N, Reuter G, Iovino N, Ribeiro C, Alenius M, Heyne S, Vavouri T, Pospisilik JA. Öst A, et al. Among authors: heyne s. Cell. 2014 Dec 4;159(6):1352-64. doi: 10.1016/j.cell.2014.11.005. Cell. 2014. PMID: 25480298 Free article.
The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes.
Lu TT, Heyne S, Dror E, Casas E, Leonhardt L, Boenke T, Yang CH, Sagar, Arrigoni L, Dalgaard K, Teperino R, Enders L, Selvaraj M, Ruf M, Raja SJ, Xie H, Boenisch U, Orkin SH, Lynn FC, Hoffman BG, Grün D, Vavouri T, Lempradl AM, Pospisilik JA. Lu TT, et al. Among authors: heyne s. Cell Metab. 2018 Jun 5;27(6):1294-1308.e7. doi: 10.1016/j.cmet.2018.04.013. Epub 2018 May 10. Cell Metab. 2018. PMID: 29754954 Free PMC article.
Independent phenotypic plasticity axes define distinct obesity sub-types.
Yang CH, Fagnocchi L, Apostle S, Wegert V, Casaní-Galdón S, Landgraf K, Panzeri I, Dror E, Heyne S, Wörpel T, Chandler DP, Lu D, Yang T, Gibbons E, Guerreiro R, Bras J, Thomasen M, Grunnet LG, Vaag AA, Gillberg L, Grundberg E, Conesa A, Körner A; PERMUTE; Pospisilik JA. Yang CH, et al. Among authors: heyne s. Nat Metab. 2022 Sep;4(9):1150-1165. doi: 10.1038/s42255-022-00629-2. Epub 2022 Sep 12. Nat Metab. 2022. PMID: 36097183 Free PMC article.
CRUP: a comprehensive framework to predict condition-specific regulatory units.
Ramisch A, Heinrich V, Glaser LV, Fuchs A, Yang X, Benner P, Schöpflin R, Li N, Kinkley S, Römer-Hillmann A, Longinotto J, Heyne S, Czepukojc B, Kessler SM, Kiemer AK, Cadenas C, Arrigoni L, Gasparoni N, Manke T, Pap T, Pospisilik JA, Hengstler J, Walter J, Meijsing SH, Chung HR, Vingron M. Ramisch A, et al. Among authors: heyne s. Genome Biol. 2019 Nov 8;20(1):227. doi: 10.1186/s13059-019-1860-7. Genome Biol. 2019. PMID: 31699133 Free PMC article.
deepTools2: a next generation web server for deep-sequencing data analysis.
Ramírez F, Ryan DP, Grüning B, Bhardwaj V, Kilpert F, Richter AS, Heyne S, Dündar F, Manke T. Ramírez F, et al. Among authors: heyne s. Nucleic Acids Res. 2016 Jul 8;44(W1):W160-5. doi: 10.1093/nar/gkw257. Epub 2016 Apr 13. Nucleic Acids Res. 2016. PMID: 27079975 Free PMC article.
Freiburg RNA tools: a central online resource for RNA-focused research and teaching.
Raden M, Ali SM, Alkhnbashi OS, Busch A, Costa F, Davis JA, Eggenhofer F, Gelhausen R, Georg J, Heyne S, Hiller M, Kundu K, Kleinkauf R, Lott SC, Mohamed MM, Mattheis A, Miladi M, Richter AS, Will S, Wolff J, Wright PR, Backofen R. Raden M, et al. Among authors: heyne s. Nucleic Acids Res. 2018 Jul 2;46(W1):W25-W29. doi: 10.1093/nar/gky329. Nucleic Acids Res. 2018. PMID: 29788132 Free PMC article.
54 results