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The immunoregulator soluble TACI is released by ADAM10 and reflects B cell activation in autoimmunity.
Hoffmann FS, Kuhn PH, Laurent SA, Hauck SM, Berer K, Wendlinger SA, Krumbholz M, Khademi M, Olsson T, Dreyling M, Pfister HW, Alexander T, Hiepe F, Kümpfel T, Crawford HC, Wekerle H, Hohlfeld R, Lichtenthaler SF, Meinl E. Hoffmann FS, et al. Among authors: hiepe f. J Immunol. 2015 Jan 15;194(2):542-52. doi: 10.4049/jimmunol.1402070. Epub 2014 Dec 10. J Immunol. 2015. PMID: 25505277 Free PMC article. Clinical Trial.
Depletion of autoreactive immunologic memory followed by autologous hematopoietic stem cell transplantation in patients with refractory SLE induces long-term remission through de novo generation of a juvenile and tolerant immune system.
Alexander T, Thiel A, Rosen O, Massenkeil G, Sattler A, Kohler S, Mei H, Radtke H, Gromnica-Ihle E, Burmester GR, Arnold R, Radbruch A, Hiepe F. Alexander T, et al. Among authors: hiepe f. Blood. 2009 Jan 1;113(1):214-23. doi: 10.1182/blood-2008-07-168286. Epub 2008 Sep 29. Blood. 2009. PMID: 18824594 Free article. Clinical Trial.
[Systemic lupus erythematosus. Target criteria for treatment].
Alexander T, Biesen R, Jacobi A, Hoyer B, Bruns A, Hiepe F. Alexander T, et al. Among authors: hiepe f. Z Rheumatol. 2009 Feb;68(1):23-9. doi: 10.1007/s00393-008-0359-5. Z Rheumatol. 2009. PMID: 19145446 Review. German.
[Plasma cells].
Hiepe F, Alexander T, Voll RE. Hiepe F, et al. Z Rheumatol. 2015 Feb;74(1):20-5. doi: 10.1007/s00393-014-1438-4. Z Rheumatol. 2015. PMID: 25616773 German.
309 results