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BHLHA15-Positive Secretory Precursor Cells Can Give Rise to Tumors in Intestine and Colon in Mice.
Hayakawa Y, Tsuboi M, Asfaha S, Kinoshita H, Niikura R, Konishi M, Hata M, Oya Y, Kim W, Middelhoff M, Hikiba Y, Higashijima N, Ihara S, Ushiku T, Fukayama M, Tailor Y, Hirata Y, Guha C, Yan KS, Koike K, Wang TC. Hayakawa Y, et al. Among authors: hikiba y. Gastroenterology. 2019 Mar;156(4):1066-1081.e16. doi: 10.1053/j.gastro.2018.11.024. Epub 2018 Nov 15. Gastroenterology. 2019. PMID: 30448068 Free PMC article.
Mature gastric chief cells are not required for the development of metaplasia.
Kinoshita H, Hayakawa Y, Niu Z, Konishi M, Hata M, Tsuboi M, Hayata Y, Hikiba Y, Ihara S, Nakagawa H, Hirata Y, Wang TC, Koike K. Kinoshita H, et al. Among authors: hikiba y. Am J Physiol Gastrointest Liver Physiol. 2018 May 1;314(5):G583-G596. doi: 10.1152/ajpgi.00351.2017. Epub 2018 Jan 18. Am J Physiol Gastrointest Liver Physiol. 2018. PMID: 29345968 Free PMC article.
Adhesive Interactions between Mononuclear Phagocytes and Intestinal Epithelium Perturb Normal Epithelial Differentiation and Serve as a Therapeutic Target in Inflammatory Bowel Disease.
Ihara S, Hirata Y, Hikiba Y, Yamashita A, Tsuboi M, Hata M, Konishi M, Suzuki N, Sakitani K, Kinoshita H, Hayakawa Y, Nakagawa H, Ijichi H, Tateishi K, Koike K. Ihara S, et al. Among authors: hikiba y. J Crohns Colitis. 2018 Nov 9;12(10):1219-1231. doi: 10.1093/ecco-jcc/jjy088. J Crohns Colitis. 2018. PMID: 29917067
Apoptosis signal-regulating kinase 1 regulates colitis and colitis-associated tumorigenesis by the innate immune responses.
Hayakawa Y, Hirata Y, Nakagawa H, Sakamoto K, Hikiba Y, Otsuka M, Ijichi H, Ikenoue T, Tateishi K, Akanuma M, Ogura K, Yoshida H, Ichijo H, Omata M, Maeda S. Hayakawa Y, et al. Among authors: hikiba y. Gastroenterology. 2010 Mar;138(3):1055-67.e1-4. doi: 10.1053/j.gastro.2009.11.015. Epub 2009 Nov 18. Gastroenterology. 2010. PMID: 19931259
Apoptosis signal-regulating kinase 1 and cyclin D1 compose a positive feedback loop contributing to tumor growth in gastric cancer.
Hayakawa Y, Hirata Y, Nakagawa H, Sakamoto K, Hikiba Y, Kinoshita H, Nakata W, Takahashi R, Tateishi K, Tada M, Akanuma M, Yoshida H, Takeda K, Ichijo H, Omata M, Maeda S, Koike K. Hayakawa Y, et al. Among authors: hikiba y. Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):780-5. doi: 10.1073/pnas.1011418108. Epub 2010 Dec 27. Proc Natl Acad Sci U S A. 2011. PMID: 21187402 Free PMC article.
Therapeutic effect of c-Jun N-terminal kinase inhibition on pancreatic cancer.
Takahashi R, Hirata Y, Sakitani K, Nakata W, Kinoshita H, Hayakawa Y, Nakagawa H, Sakamoto K, Hikiba Y, Ijichi H, Moses HL, Maeda S, Koike K. Takahashi R, et al. Among authors: hikiba y. Cancer Sci. 2013 Mar;104(3):337-44. doi: 10.1111/cas.12080. Epub 2013 Jan 24. Cancer Sci. 2013. PMID: 23237571 Free PMC article.
59 results