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Parkinson's disease-associated iPLA2-VIA/PLA2G6 regulates neuronal functions and α-synuclein stability through membrane remodeling.
Mori A, Hatano T, Inoshita T, Shiba-Fukushima K, Koinuma T, Meng H, Kubo SI, Spratt S, Cui C, Yamashita C, Miki Y, Yamamoto K, Hirabayashi T, Murakami M, Takahashi Y, Shindou H, Nonaka T, Hasegawa M, Okuzumi A, Imai Y, Hattori N. Mori A, et al. Among authors: hirabayashi t. Proc Natl Acad Sci U S A. 2019 Oct 8;116(41):20689-20699. doi: 10.1073/pnas.1902958116. Epub 2019 Sep 23. Proc Natl Acad Sci U S A. 2019. PMID: 31548400 Free PMC article.
Analysis of two major intracellular phospholipases A(2) (PLA(2)) in mast cells reveals crucial contribution of cytosolic PLA(2)α, not Ca(2+)-independent PLA(2)β, to lipid mobilization in proximal mast cells and distal fibroblasts.
Ueno N, Taketomi Y, Yamamoto K, Hirabayashi T, Kamei D, Kita Y, Shimizu T, Shinzawa K, Tsujimoto Y, Ikeda K, Taguchi R, Murakami M. Ueno N, et al. Among authors: hirabayashi t. J Biol Chem. 2011 Oct 28;286(43):37249-63. doi: 10.1074/jbc.M111.290312. Epub 2011 Aug 31. J Biol Chem. 2011. PMID: 21880721 Free PMC article.
The adipocyte-inducible secreted phospholipases PLA2G5 and PLA2G2E play distinct roles in obesity.
Sato H, Taketomi Y, Ushida A, Isogai Y, Kojima T, Hirabayashi T, Miki Y, Yamamoto K, Nishito Y, Kobayashi T, Ikeda K, Taguchi R, Hara S, Ida S, Miyamoto Y, Watanabe M, Baba H, Miyata K, Oike Y, Gelb MH, Murakami M. Sato H, et al. Among authors: hirabayashi t. Cell Metab. 2014 Jul 1;20(1):119-32. doi: 10.1016/j.cmet.2014.05.002. Epub 2014 Jun 5. Cell Metab. 2014. PMID: 24910243 Free PMC article.
Hepatic phosphatidylcholine catabolism driven by PNPLA7 and PNPLA8 supplies endogenous choline to replenish the methionine cycle with methyl groups.
Hirabayashi T, Kawaguchi M, Harada S, Mouri M, Takamiya R, Miki Y, Sato H, Taketomi Y, Yokoyama K, Kobayashi T, Tokuoka SM, Kita Y, Yoda E, Hara S, Mikami K, Nishito Y, Kikuchi N, Nakata R, Kaneko M, Kiyonari H, Kasahara K, Aiba T, Ikeda K, Soga T, Kurano M, Yatomi Y, Murakami M. Hirabayashi T, et al. Cell Rep. 2023 Feb 28;42(2):111940. doi: 10.1016/j.celrep.2022.111940. Epub 2023 Jan 30. Cell Rep. 2023. PMID: 36719796 Free article.
354 results