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Free fatty acids inhibit serum deprivation-induced apoptosis through GPR120 in a murine enteroendocrine cell line STC-1.
Katsuma S, Hatae N, Yano T, Ruike Y, Kimura M, Hirasawa A, Tsujimoto G. Katsuma S, et al. Among authors: hirasawa a. J Biol Chem. 2005 May 20;280(20):19507-15. doi: 10.1074/jbc.M412385200. Epub 2005 Mar 17. J Biol Chem. 2005. PMID: 15774482
Free fatty acids (FFAs) provide an important energy source and also act as signaling molecules. FFAs are known to exert a variety of physiological responses via their G protein-coupled receptors (GPCRs), such as the GPR40 family. Recently, we identified a novel FFA …
Free fatty acids (FFAs) provide an important energy source and also act as signaling molecules. FFAs are known to exert a variety of …
Free fatty acids induce cholecystokinin secretion through GPR120.
Tanaka T, Katsuma S, Adachi T, Koshimizu TA, Hirasawa A, Tsujimoto G. Tanaka T, et al. Among authors: hirasawa a. Naunyn Schmiedebergs Arch Pharmacol. 2008 Jun;377(4-6):523-7. doi: 10.1007/s00210-007-0200-8. Epub 2007 Oct 31. Naunyn Schmiedebergs Arch Pharmacol. 2008. PMID: 17972064
Cloning and characterization of the rat free fatty acid receptor GPR120: in vivo effect of the natural ligand on GLP-1 secretion and proliferation of pancreatic beta cells.
Tanaka T, Yano T, Adachi T, Koshimizu TA, Hirasawa A, Tsujimoto G. Tanaka T, et al. Among authors: hirasawa a. Naunyn Schmiedebergs Arch Pharmacol. 2008 Jun;377(4-6):515-22. doi: 10.1007/s00210-007-0250-y. Epub 2008 Mar 5. Naunyn Schmiedebergs Arch Pharmacol. 2008. PMID: 18320172
We have recently found that GPR120, which is abundantly expressed in intestine, functions as a receptor for unsaturated long-chain free fatty acids (FFAs) and that GPR120 stimulation promotes the secretion of glucagons-like peptide-1 (GLP-1) in the mouse (Hirasawa e …
We have recently found that GPR120, which is abundantly expressed in intestine, functions as a receptor for unsaturated long-chain fr …
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