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Truncated carboxyl-terminal fragments of beta-amyloid precursor protein are processed to amyloid beta-proteins 40 and 42.
Biochemistry. 2004 Oct 26;43(42):13532-40. doi: 10.1021/bi049399k.
Biochemistry. 2004.
PMID: 15491160
Longer forms of amyloid beta protein: implications for the mechanism of intramembrane cleavage by gamma-secretase.
Qi-Takahara Y, Morishima-Kawashima M, Tanimura Y, Dolios G, Hirotani N, Horikoshi Y, Kametani F, Maeda M, Saido TC, Wang R, Ihara Y.
Qi-Takahara Y, et al. Among authors: hirotani n.
J Neurosci. 2005 Jan 12;25(2):436-45. doi: 10.1523/JNEUROSCI.1575-04.2005.
J Neurosci. 2005.
PMID: 15647487
Free PMC article.
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Blocking the cleavage at midportion between gamma- and epsilon-sites remarkably suppresses the generation of amyloid beta-protein.
Sato T, Tanimura Y, Hirotani N, Saido TC, Morishima-Kawashima M, Ihara Y.
Sato T, et al. Among authors: hirotani n.
FEBS Lett. 2005 May 23;579(13):2907-12. doi: 10.1016/j.febslet.2005.04.037.
FEBS Lett. 2005.
PMID: 15890346
Free article.
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