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CaMKII activates ASK1 and NF-kappaB to induce cardiomyocyte hypertrophy.
Kashiwase K, Higuchi Y, Hirotani S, Yamaguchi O, Hikoso S, Takeda T, Watanabe T, Taniike M, Nakai A, Tsujimoto I, Matsumura Y, Ueno H, Nishida K, Hori M, Otsu K. Kashiwase K, et al. Among authors: hirotani s. Biochem Biophys Res Commun. 2005 Feb 4;327(1):136-42. doi: 10.1016/j.bbrc.2004.12.002. Biochem Biophys Res Commun. 2005. PMID: 15629441
Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis.
Yamaguchi O, Watanabe T, Nishida K, Kashiwase K, Higuchi Y, Takeda T, Hikoso S, Hirotani S, Asahi M, Taniike M, Nakai A, Tsujimoto I, Matsumura Y, Miyazaki J, Chien KR, Matsuzawa A, Sadamitsu C, Ichijo H, Baccarini M, Hori M, Otsu K. Yamaguchi O, et al. Among authors: hirotani s. J Clin Invest. 2004 Oct;114(7):937-43. doi: 10.1172/JCI20317. J Clin Invest. 2004. PMID: 15467832 Free PMC article.
The small GTP-binding protein Rac1 induces cardiac myocyte hypertrophy through the activation of apoptosis signal-regulating kinase 1 and nuclear factor-kappa B.
Higuchi Y, Otsu K, Nishida K, Hirotani S, Nakayama H, Yamaguchi O, Hikoso S, Kashiwase K, Takeda T, Watanabe T, Mano T, Matsumura Y, Ueno H, Hori M. Higuchi Y, et al. Among authors: hirotani s. J Biol Chem. 2003 Jun 6;278(23):20770-7. doi: 10.1074/jbc.M213203200. Epub 2003 Apr 2. J Biol Chem. 2003. PMID: 12672819 Free article.
Targeted deletion of apoptosis signal-regulating kinase 1 attenuates left ventricular remodeling.
Yamaguchi O, Higuchi Y, Hirotani S, Kashiwase K, Nakayama H, Hikoso S, Takeda T, Watanabe T, Asahi M, Taniike M, Matsumura Y, Tsujimoto I, Hongo K, Kusakari Y, Kurihara S, Nishida K, Ichijo H, Hori M, Otsu K. Yamaguchi O, et al. Among authors: hirotani s. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15883-8. doi: 10.1073/pnas.2136717100. Epub 2003 Dec 9. Proc Natl Acad Sci U S A. 2003. PMID: 14665690 Free PMC article.
p38alpha mitogen-activated protein kinase plays a critical role in cardiomyocyte survival but not in cardiac hypertrophic growth in response to pressure overload.
Nishida K, Yamaguchi O, Hirotani S, Hikoso S, Higuchi Y, Watanabe T, Takeda T, Osuka S, Morita T, Kondoh G, Uno Y, Kashiwase K, Taniike M, Nakai A, Matsumura Y, Miyazaki J, Sudo T, Hongo K, Kusakari Y, Kurihara S, Chien KR, Takeda J, Hori M, Otsu K. Nishida K, et al. Among authors: hirotani s. Mol Cell Biol. 2004 Dec;24(24):10611-20. doi: 10.1128/MCB.24.24.10611-10620.2004. Mol Cell Biol. 2004. PMID: 15572667 Free PMC article.
85 results