Hirst TR - Search Results

1

Proteolytic activation of cholera toxin and Escherichia coli labile toxin by entry into host epithelial cells. Signal transduction by a protease-resistant toxin variant.

Lencer WI, Constable C, Moe S, Rufo PA, Wolf A, Jobling MG, Ruston SP, Madara JL, Holmes RK, Hirst TR. Lencer WI, et al. Among authors: hirst tr. J Biol Chem. 1997 Jun 13;272(24):15562-8. doi: 10.1074/jbc.272.24.15562. J Biol Chem. 1997. PMID: 9182593 Free article.

2

Targeting of cholera toxin and Escherichia coli heat labile toxin in polarized epithelia: role of COOH-terminal KDEL.

Lencer WI, Constable C, Moe S, Jobling MG, Webb HM, Ruston S, Madara JL, Hirst TR, Holmes RK. Lencer WI, et al. Among authors: hirst tr. J Cell Biol. 1995 Nov;131(4):951-62. doi: 10.1083/jcb.131.4.951. J Cell Biol. 1995. PMID: 7490296 Free PMC article.

3

Kinetics of acid-mediated disassembly of the B subunit pentamer of Escherichia coli heat-labile enterotoxin. Molecular basis of pH stability.

Ruddock LW, Ruston SP, Kelly SM, Price NC, Freedman RB, Hirst TR. Ruddock LW, et al. Among authors: hirst tr. J Biol Chem. 1995 Dec 15;270(50):29953-8. doi: 10.1074/jbc.270.50.29953. J Biol Chem. 1995. PMID: 8530395 Free article.

4

Structural basis for the differential toxicity of cholera toxin and Escherichia coli heat-labile enterotoxin. Construction of hybrid toxins identifies the A2-domain as the determinant of differential toxicity.

Rodighiero C, Aman AT, Kenny MJ, Moss J, Lencer WI, Hirst TR. Rodighiero C, et al. Among authors: hirst tr. J Biol Chem. 1999 Feb 12;274(7):3962-9. doi: 10.1074/jbc.274.7.3962. J Biol Chem. 1999. PMID: 9933586 Free article.

5

Membrane traffic and the cellular uptake of cholera toxin.

Lencer WI, Hirst TR, Holmes RK. Lencer WI, et al. Among authors: hirst tr. Biochim Biophys Acta. 1999 Jul 8;1450(3):177-90. doi: 10.1016/s0167-4889(99)00070-1. Biochim Biophys Acta. 1999. PMID: 10395933 Free article. Review.

6

Floating cholera toxin into epithelial cells: functional association with caveolae-like detergent-insoluble membrane microdomains.

Badizadegan K, Wolf AA, Rodighiero C, Jobling M, Hirst TR, Holmes RK, Lencer WI. Badizadegan K, et al. Among authors: hirst tr. Int J Med Microbiol. 2000 Oct;290(4-5):403-8. doi: 10.1016/S1438-4221(00)80052-1. Int J Med Microbiol. 2000. PMID: 11111918 Review.

7

A cholera toxin B-subunit variant that binds ganglioside G(M1) but fails to induce toxicity.

Rodighiero C, Fujinaga Y, Hirst TR, Lencer WI. Rodighiero C, et al. Among authors: hirst tr. J Biol Chem. 2001 Oct 5;276(40):36939-45. doi: 10.1074/jbc.M104245200. Epub 2001 Jul 30. J Biol Chem. 2001. PMID: 11479294 Free article.

8

Structural studies of receptor binding by cholera toxin mutants.

Merritt EA, Sarfaty S, Jobling MG, Chang T, Holmes RK, Hirst TR, Hol WG. Merritt EA, et al. Among authors: hirst tr. Protein Sci. 1997 Jul;6(7):1516-28. doi: 10.1002/pro.5560060716. Protein Sci. 1997. PMID: 9232653 Free PMC article.

9

A pH-dependent conformational change in the B-subunit pentamer of Escherichia coli heat-labile enterotoxin: structural basis and possible functional role for a conserved feature of the AB5 toxin family.

Ruddock LW, Webb HM, Ruston SP, Cheesman C, Freedman RB, Hirst TR. Ruddock LW, et al. Among authors: hirst tr. Biochemistry. 1996 Dec 17;35(50):16069-76. doi: 10.1021/bi961865l. Biochemistry. 1996. PMID: 8973177

10

Differential activity of cholera toxin and E. coli enterotoxin: construction and purification of mutant and hybrid derivatives.

Rodighiero C, Aman AT, Lencer WI, Hirst TR. Rodighiero C, et al. Among authors: hirst tr. Biochem Soc Trans. 1998 Nov;26(4):S364. doi: 10.1042/bst026s364. Biochem Soc Trans. 1998. PMID: 10047878 No abstract available.

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