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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 2
1977 4
1978 5
1979 10
1980 2
1981 11
1982 7
1983 6
1984 9
1985 13
1986 8
1987 11
1988 5
1989 7
1990 9
1991 7
1992 12
1993 10
1994 12
1995 12
1996 8
1997 14
1998 13
1999 14
2000 9
2001 10
2002 15
2003 17
2004 13
2005 12
2006 14
2007 12
2008 15
2009 22
2010 11
2011 10
2012 13
2013 22
2014 14
2015 9
2016 12
2017 15
2018 26
2019 35
2020 31
2021 35
2022 16
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547 results
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Page 1
Bioinformatics analysis of the prognosis and biological significance of HMGB1, HMGB2, and HMGB3 in gastric cancer.
Fang J, Ge X, Xu W, Xie J, Qin Z, Shi L, Yin W, Bian M, Wang H. Fang J, et al. J Cell Physiol. 2020 Apr;235(4):3438-3446. doi: 10.1002/jcp.29233. Epub 2019 Oct 16. J Cell Physiol. 2020. PMID: 31621076
Correlations between HMGB1, HMGB2, and HMGB3 and clinicopathological factors were analyzed. cBioPortal was used to analyze HMGB1, HMGB2, and HMGB3 genetic alterations and its gene regulation network in GC tissue. ...High HMGB1, HMGB2, and HMGB3 expression may …
Correlations between HMGB1, HMGB2, and HMGB3 and clinicopathological factors were analyzed. cBioPortal was used to analyze HMGB1, …
HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and Induces CTCF Clustering across Cell Types.
Zirkel A, Nikolic M, Sofiadis K, Mallm JP, Brackley CA, Gothe H, Drechsel O, Becker C, Altmüller J, Josipovic N, Georgomanolis T, Brant L, Franzen J, Koker M, Gusmao EG, Costa IG, Ullrich RT, Wagner W, Roukos V, Nürnberg P, Marenduzzo D, Rippe K, Papantonis A. Zirkel A, et al. Mol Cell. 2018 May 17;70(4):730-744.e6. doi: 10.1016/j.molcel.2018.03.030. Epub 2018 Apr 26. Mol Cell. 2018. PMID: 29706538 Free article.
Knocking down HMGB2 suffices for senescence-induced CTCF clustering and for loop reshuffling, while ectopically expressing HMGB2 rescues these effects. Our data suggest that HMGB2-mediated genomic reorganization constitutes a primer for the ensuing senescent …
Knocking down HMGB2 suffices for senescence-induced CTCF clustering and for loop reshuffling, while ectopically expressing HMGB2 …
HMGB2 orchestrates mitotic clonal expansion by binding to the promoter of C/EBPβ to facilitate adipogenesis.
Chen K, Zhang J, Liang F, Zhu Q, Cai S, Tong X, He Z, Liu X, Chen Y, Mo D. Chen K, et al. Cell Death Dis. 2021 Jul 2;12(7):666. doi: 10.1038/s41419-021-03959-3. Cell Death Dis. 2021. PMID: 34215724 Free PMC article.
High-mobility group box 2 (HMGB2) is an abundant, chromatin-associated protein that plays an essential role in the regulation of transcription, cell proliferation, differentiation, and tumorigenesis. However, the underlying mechanism of HMGB2 in adipogenesis …
High-mobility group box 2 (HMGB2) is an abundant, chromatin-associated protein that plays an essential role in the regulation …
HMGB2 promotes the malignancy of human gastric cancer and indicates poor survival outcome.
Cui G, Cai F, Ding Z, Gao L. Cui G, et al. Hum Pathol. 2019 Feb;84:133-141. doi: 10.1016/j.humpath.2018.09.017. Epub 2018 Oct 5. Hum Pathol. 2019. PMID: 30296520
HMGB2 is an important protein in carcinogenesis. However, little is known about the specific role of HMGB2 in gastric cancer. ...The effect of HMGB2 on cell proliferation, invasion, and glycolysis was examined in vitro. ...
HMGB2 is an important protein in carcinogenesis. However, little is known about the specific role of HMGB2 in gastric cancer. …
HMGB2 is associated with pressure loading in chondrocytes of temporomandibular joint: In vitro and in vivo study.
Zhou Y, Lu H, Deng L, Lin CH, Pennington Klein K, Wu M. Zhou Y, et al. Cytokine. 2020 Feb;126:154875. doi: 10.1016/j.cyto.2019.154875. Epub 2019 Oct 16. Cytokine. 2020. PMID: 31629102
The results indicated that HP decreased the mRNA expression of HMGB2, MMP-13, and beta-catenin. HMGB2 knockdown attenuated the sensitivity of chondrocytes response to pressure loading. ...In rabbit cartilage with ADD, the expression of HMGB2 and beta-catenin …
The results indicated that HP decreased the mRNA expression of HMGB2, MMP-13, and beta-catenin. HMGB2 knockdown attenuated the …
HMGB2 is a negative regulator of telomerase activity in human embryonic stem and progenitor cells.
Kučírek M, Bagherpoor AJ, Jaroš J, Hampl A, Štros M. Kučírek M, et al. FASEB J. 2019 Dec 1;33(12):14307-14324. doi: 10.1096/fj.201901465RRR. Epub 2019 Oct 26. FASEB J. 2019. PMID: 31661640
Using inducible, stably transfected human embryonic stem cells (hESCs) capable of the short hairpin RNA-mediated knockdown (KD) of HMGB1 and HMGB2, we provide evidence that deregulation of HMGB1 or HMGB2 expression in hESCs and their differentiated derivatives (neur …
Using inducible, stably transfected human embryonic stem cells (hESCs) capable of the short hairpin RNA-mediated knockdown (KD) of HMGB1 and …
Knockdown of HMGB2 inhibits proliferation and invasion of renal tumor cells via the p-38MAPK pathway.
He ZH, Guo F, Hu XX, Luo ZY, Yi JW. He ZH, et al. Eur Rev Med Pharmacol Sci. 2020 May;24(9):4729-4737. doi: 10.26355/eurrev_202005_21161. Eur Rev Med Pharmacol Sci. 2020. PMID: 32432736 Free article.
Down-regulation of HMGB2 suppressed ACHN cells proliferation, invasion and migration in vitro. Moreover, down-regulation of HMGB2 inhibited tumor growth in vivo and HMGB2 exerts the oncogene function partly via the inhibition of p-p38MAPK activation. ...
Down-regulation of HMGB2 suppressed ACHN cells proliferation, invasion and migration in vitro. Moreover, down-regulation of HMGB2 …
HMGB2 promotes chondrocyte proliferation under negative pressure through the phosphorylation of AKT.
Liu Q, He F, Zhou P, Xie M, Wang H, Yang H, Huo W, Zhang M, Yu S, Wang M. Liu Q, et al. Biochim Biophys Acta Mol Cell Res. 2021 Oct;1868(11):119115. doi: 10.1016/j.bbamcr.2021.119115. Epub 2021 Jul 30. Biochim Biophys Acta Mol Cell Res. 2021. PMID: 34333060
Data from RNA-sequencing analysis indicated that the superficial chondrocytes responded to the 4 h -10 kPa treatment by a significant increase in proliferation. In addition, the expression of high-mobility group box 2 (HMGB2) and the phosphorylation of AKT were obvi …
Data from RNA-sequencing analysis indicated that the superficial chondrocytes responded to the 4 h -10 kPa treatment by a significant increa …
Nonhistone Proteins HMGB1 and HMGB2 Differentially Modulate the Response of Human Embryonic Stem Cells and the Progenitor Cells to the Anticancer Drug Etoposide.
Bagherpoor AJ, Kučírek M, Fedr R, Sani SA, Štros M. Bagherpoor AJ, et al. Biomolecules. 2020 Oct 15;10(10):1450. doi: 10.3390/biom10101450. Biomolecules. 2020. PMID: 33076532 Free PMC article.
On the other hand, decreased accumulation of 53BP1 on telomeres in etoposide-treated HMGB2 KD hESCs (but not in HMGB2 KD hNECs) suggested that the loss of HMGB2 promoted the stability of telomeres. Etoposide treatment of hESCs resulted in a significant enhanc …
On the other hand, decreased accumulation of 53BP1 on telomeres in etoposide-treated HMGB2 KD hESCs (but not in HMGB2 KD hNECs …
HMGB2 regulates satellite-cell-mediated skeletal muscle regeneration through IGF2BP2.
Zhou X, Li M, Huang H, Chen K, Yuan Z, Zhang Y, Nie Y, Chen H, Zhang X, Chen L, Chen Y, Mo D. Zhou X, et al. J Cell Sci. 2016 Nov 15;129(22):4305-4316. doi: 10.1242/jcs.189944. Epub 2016 Sep 26. J Cell Sci. 2016. PMID: 27672022
HMGB2 was highly expressed in undifferentiated myoblasts and regenerating muscle. ...HMGB2 depletion downregulated Myf5 and cyclin A2 at the protein but not mRNA level. ...
HMGB2 was highly expressed in undifferentiated myoblasts and regenerating muscle. ...HMGB2 depletion downregulated Myf5 and cy …
547 results