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Tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces cell proliferation in normal human bronchial epithelial cells through NFkappaB activation and cyclin D1 up-regulation.
Ho YS, Chen CH, Wang YJ, Pestell RG, Albanese C, Chen RJ, Chang MC, Jeng JH, Lin SY, Liang YC, Tseng H, Lee WS, Lin JK, Chu JS, Chen LC, Lee CH, Tso WL, Lai YC, Wu CH. Ho YS, et al. Toxicol Appl Pharmacol. 2005 Jun 1;205(2):133-48. doi: 10.1016/j.taap.2004.09.019. Epub 2005 Jan 8. Toxicol Appl Pharmacol. 2005. PMID: 15893541
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