Hobbs AJ - Search Results

1

BAY41-2272, a novel nitric oxide independent soluble guanylate cyclase activator, relaxes human and rabbit corpus cavernosum in vitro.

Kalsi JS, Rees RW, Hobbs AJ, Royle M, Kell PD, Ralph DJ, Moncada S, Cellek S. Kalsi JS, et al. Among authors: hobbs aj. J Urol. 2003 Feb;169(2):761-6. doi: 10.1097/01.ju.0000043880.58140.69. J Urol. 2003. PMID: 12544359

2

L-NG-nitro-arginine and its methyl ester are potent inhibitors of non-adrenergic, non-cholinergic transmission in the rat anococcygeus.

Hobbs AJ, Gibson A. Hobbs AJ, et al. Br J Pharmacol. 1990 Aug;100(4):749-52. doi: 10.1111/j.1476-5381.1990.tb14086.x. Br J Pharmacol. 1990. PMID: 2169939 Free PMC article.

3

Soluble guanylate cyclase: the forgotten sibling.

Hobbs AJ. Hobbs AJ. Trends Pharmacol Sci. 1997 Dec;18(12):484-91. doi: 10.1016/s0165-6147(97)01137-1. Trends Pharmacol Sci. 1997. PMID: 9458697 Review.

4

Inhibition of nitric oxide synthase as a potential therapeutic target.

Hobbs AJ, Higgs A, Moncada S. Hobbs AJ, et al. Annu Rev Pharmacol Toxicol. 1999;39:191-220. doi: 10.1146/annurev.pharmtox.39.1.191. Annu Rev Pharmacol Toxicol. 1999. PMID: 10331082 Review.

5

Biochemical characterization of S-nitrosohemoglobin. Mechanisms underlying synthesis, no release, and biological activity.

Wolzt M, MacAllister RJ, Davis D, Feelisch M, Moncada S, Vallance P, Hobbs AJ. Wolzt M, et al. Among authors: hobbs aj. J Biol Chem. 1999 Oct 8;274(41):28983-90. doi: 10.1074/jbc.274.41.28983. J Biol Chem. 1999. PMID: 10506146 Free article.

6

Autoregulation of nitric oxide-soluble guanylate cyclase-cyclic GMP signalling in mouse thoracic aorta.

Hussain MB, Hobbs AJ, MacAllister RJ. Hussain MB, et al. Among authors: hobbs aj. Br J Pharmacol. 1999 Nov;128(5):1082-8. doi: 10.1038/sj.bjp.0702874. Br J Pharmacol. 1999. PMID: 10556946 Free PMC article.

7

Synthesis and biological evaluation of novel pyrazoles and indazoles as activators of the nitric oxide receptor, soluble guanylate cyclase.

Selwood DL, Brummell DG, Budworth J, Burtin GE, Campbell RO, Chana SS, Charles IG, Fernandez PA, Glen RC, Goggin MC, Hobbs AJ, Kling MR, Liu Q, Madge DJ, Meillerais S, Powell KL, Reynolds K, Spacey GD, Stables JN, Tatlock MA, Wheeler KA, Wishart G, Woo CK. Selwood DL, et al. Among authors: hobbs aj. J Med Chem. 2001 Jan 4;44(1):78-93. doi: 10.1021/jm001034k. J Med Chem. 2001. PMID: 11141091

8

Reciprocal regulation of cGMP-mediated vasorelaxation by soluble and particulate guanylate cyclases.

Hussain MB, MacAllister RJ, Hobbs AJ. Hussain MB, et al. Among authors: hobbs aj. Am J Physiol Heart Circ Physiol. 2001 Mar;280(3):H1151-9. doi: 10.1152/ajpheart.2001.280.3.H1151. Am J Physiol Heart Circ Physiol. 2001. PMID: 11179059 Free article.

9

Biphasic regulation of NF-kappa B activity underlies the pro- and anti-inflammatory actions of nitric oxide.

Connelly L, Palacios-Callender M, Ameixa C, Moncada S, Hobbs AJ. Connelly L, et al. Among authors: hobbs aj. J Immunol. 2001 Mar 15;166(6):3873-81. doi: 10.4049/jimmunol.166.6.3873. J Immunol. 2001. PMID: 11238631

10

Macrophage endothelial nitric-oxide synthase autoregulates cellular activation and pro-inflammatory protein expression.

Connelly L, Jacobs AT, Palacios-Callender M, Moncada S, Hobbs AJ. Connelly L, et al. Among authors: hobbs aj. J Biol Chem. 2003 Jul 18;278(29):26480-7. doi: 10.1074/jbc.M302238200. Epub 2003 May 9. J Biol Chem. 2003. PMID: 12740377 Free article.

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