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All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins.
Hochbaum DR, Zhao Y, Farhi SL, Klapoetke N, Werley CA, Kapoor V, Zou P, Kralj JM, Maclaurin D, Smedemark-Margulies N, Saulnier JL, Boulting GL, Straub C, Cho YK, Melkonian M, Wong GK, Harrison DJ, Murthy VN, Sabatini BL, Boyden ES, Campbell RE, Cohen AE. Hochbaum DR, et al. Nat Methods. 2014 Aug;11(8):825-33. doi: 10.1038/nmeth.3000. Epub 2014 Jun 22. Nat Methods. 2014. PMID: 24952910 Free PMC article.
Roadmap on neurophotonics.
Cho YK, Zheng G, Augustine GJ, Hochbaum D, Cohen A, Knöpfel T, Pisanello F, Pavone FS, Vellekoop IM, Booth MJ, Hu S, Zhu J, Chen Z, Hoshi Y. Cho YK, et al. J Opt. 2016 Sep;18(9):093007. doi: 10.1088/2040-8978/18/9/093007. Epub 2016 Aug 18. J Opt. 2016. PMID: 28386392 Free PMC article.
A robotic multidimensional directed evolution approach applied to fluorescent voltage reporters.
Piatkevich KD, Jung EE, Straub C, Linghu C, Park D, Suk HJ, Hochbaum DR, Goodwin D, Pnevmatikakis E, Pak N, Kawashima T, Yang CT, Rhoades JL, Shemesh O, Asano S, Yoon YG, Freifeld L, Saulnier JL, Riegler C, Engert F, Hughes T, Drobizhev M, Szabo B, Ahrens MB, Flavell SW, Sabatini BL, Boyden ES. Piatkevich KD, et al. Among authors: hochbaum dr. Nat Chem Biol. 2018 Apr;14(4):352-360. doi: 10.1038/s41589-018-0004-9. Epub 2018 Feb 26. Nat Chem Biol. 2018. PMID: 29483642 Free PMC article.
Activity-dependent regulome of human GABAergic neurons reveals new patterns of gene regulation and neurological disease heritability.
Boulting GL, Durresi E, Ataman B, Sherman MA, Mei K, Harmin DA, Carter AC, Hochbaum DR, Granger AJ, Engreitz JM, Hrvatin S, Blanchard MR, Yang MG, Griffith EC, Greenberg ME. Boulting GL, et al. Among authors: hochbaum dr. Nat Neurosci. 2021 Mar;24(3):437-448. doi: 10.1038/s41593-020-00786-1. Epub 2021 Feb 4. Nat Neurosci. 2021. PMID: 33542524 Free PMC article.
29 results