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Misfolded proinsulin affects bystander proinsulin in neonatal diabetes.
Hodish I, Liu M, Rajpal G, Larkin D, Holz RW, Adams A, Liu L, Arvan P. Hodish I, et al. J Biol Chem. 2010 Jan 1;285(1):685-94. doi: 10.1074/jbc.M109.038042. Epub 2009 Oct 30. J Biol Chem. 2010. PMID: 19880509 Free PMC article.
It has previously been shown that misfolded mutant Akita proinsulin in the endoplasmic reticulum engages directly in protein complexes either with nonmutant proinsulin or with "hProCpepGFP" (human proinsulin bearing emerald-GFP within the C-peptide), impairing the trafficking of …
It has previously been shown that misfolded mutant Akita proinsulin in the endoplasmic reticulum engages directly in protein complexes eithe …
Proinsulin misfolding and diabetes: mutant INS gene-induced diabetes of youth.
Liu M, Hodish I, Haataja L, Lara-Lemus R, Rajpal G, Wright J, Arvan P. Liu M, et al. Among authors: hodish i. Trends Endocrinol Metab. 2010 Nov;21(11):652-9. doi: 10.1016/j.tem.2010.07.001. Epub 2010 Aug 18. Trends Endocrinol Metab. 2010. PMID: 20724178 Free PMC article. Review.
Insulin therapy, weight gain and prognosis.
Hodish I. Hodish I. Diabetes Obes Metab. 2018 Sep;20(9):2085-2092. doi: 10.1111/dom.13367. Epub 2018 Jun 22. Diabetes Obes Metab. 2018. PMID: 29785843 Free article. Review.
Insulin requirements are eternally dynamic.
Hodish I. Hodish I. Diabetes Obes Metab. 2021 Oct;23(10):2409-2410. doi: 10.1111/dom.14460. Epub 2021 Jul 19. Diabetes Obes Metab. 2021. PMID: 34105237 No abstract available.
Proinsulin maturation, misfolding, and proteotoxicity.
Liu M, Hodish I, Rhodes CJ, Arvan P. Liu M, et al. Among authors: hodish i. Proc Natl Acad Sci U S A. 2007 Oct 2;104(40):15841-6. doi: 10.1073/pnas.0702697104. Epub 2007 Sep 26. Proc Natl Acad Sci U S A. 2007. PMID: 17898179 Free PMC article.
Are glucose readings sufficient to adjust insulin dosage?
Bashan E, Herman WH, Hodish I. Bashan E, et al. Among authors: hodish i. Diabetes Technol Ther. 2011 Jan;13(1):85-92. doi: 10.1089/dia.2010.0112. Diabetes Technol Ther. 2011. PMID: 21175277 Free article. Clinical Trial.
41 results